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Tympanic Paraganglioma

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Contemporary Management of Jugular Paraganglioma

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Abstract

Tympanic paragangliomas (TP) are the most common, benign primary tumors of the middle ear. They originate along the tympanic plexus associated with Jacobson’s (IX) and Arnold’s (X) nerves and are comprised of paraganglion cells derived from the neural crest. This class of tumors can be found throughout the body, though in the temporal bone, two forms are predominantly seen depending on the site of origin: tympanic (tympanic paraganglioma, TP) and jugular (jugular paraganglioma, JP), the latter of which arises from the adventitia of the jugular bulb. Like many other types of paraganglioma tumors in the head and neck, TP are highly vascular, and within the small confines of the tympanic and mastoid cavity, excision can be a complicated endeavor. Furthermore, the growing body of information regarding tumor biology is beginning to influence diagnostic and management paradigms. The following chapter reviews some of the most salient aspects of TP diagnosis and management.

Financial Material and Support: Internal departmental funding was utilized without commercial sponsorship or support. Conflict(s) of Interest to Declare: There are no relevant disclosures.

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Abbreviations

CSF:

Cerebrospinal fluid

CT:

Computed tomography

EAC:

External auditory canal

GT:

Glomus tympanicum

JP:

Jugular paraganglioma

MRI:

Magnetic resonance imaging

TP:

Tympanic paraganglioma

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Author information

Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Baylor Plaza, Houston, TX, 77030, USA

    Alex D. Sweeney M.D.

  2. Department of Otolaryngology, Mayo Clinic School of Medicine, Rochester, NY, USA

    Matthew L. Carlson M.D.

Authors
  1. Alex D. Sweeney M.D.
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  2. Matthew L. Carlson M.D.
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Corresponding author

Correspondence to Alex D. Sweeney M.D. .

Editor information

Editors and Affiliations

  1. Department of Otolaryngology, Mount Sinai Health System, New York, New York, USA

    George B. Wanna

  2. Department of Otolaryngology, Mayo Clinic School of Medicine, Rochester, New York, USA

    Matthew L. Carlson

  3. Center for Otolaryngology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

    James L. Netterville

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Sweeney, A.D., Carlson, M.L. (2018). Tympanic Paraganglioma. In: Wanna, G., Carlson, M., Netterville, J. (eds) Contemporary Management of Jugular Paraganglioma. Springer, Cham. https://doi.org/10.1007/978-3-319-60955-3_11

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  • DOI: https://doi.org/10.1007/978-3-319-60955-3_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-60954-6

  • Online ISBN: 978-3-319-60955-3

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