Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Breast Cancer Treatment in Young Women

  • Chapter
  • First Online:
Changing Paradigms in the Management of Breast Cancer

  • 931 Accesses

Abstract

Young women diagnosed with breast cancer present many unique challenges, both in treatment and in terms of management. Some of these considerations include genetic evaluation for cancer predisposing mutations, fertility preservation, and psychosocial issues. The constellation of all of these factors make younger patients with breast cancer require a multidisciplinary team.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  1. Sonmezer M, Oktay K. Fertility preservation in young women undergoing breast cancer therapy. The Oncologist. 2006;11(5):422–34.

    Article  CAS  PubMed  Google Scholar 

  2. Brinton LA, Sherman ME, Carreon JD, Anderson WF. Recent trends in breast cancer among younger women in the United States. J Natl Cancer Inst. 2008;100:1643.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Waks AG, Partridge AH. Fertility preservation in patients with breast cancer: necessity, methods, and safety. J Natl Compr Cancer Netw. 2016;14(3):355–63.

    Article  CAS  Google Scholar 

  4. Bellcross CA, et al. Evaluation of a breast/ovarian cancer genetics referral screening tool in a mammography population. Genet Med. 2009;11.11:783–9.

    Article  Google Scholar 

  5. Antoniou A, et al. Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72(5):1117–30.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Hall MJ, et al. Gene panel testing for inherited cancer risk. J Natl Cancer Netw. 2014;12(9):1339–46.

    Article  Google Scholar 

  7. Tung, Nadine, Battelli, Chiara, Allen, Brian, et al.. Prevalence of gene mutations among hereditary breast and ovarian cancer patients using a 25 gene panel. Beth Israel Deaconess Medical Center. Presented at San Antonio Breast Cancer Symposium, December 2013.

    Google Scholar 

  8. Davies C, Pan H, Godwin J, Gray R, Arriagada R, Raina V, et al. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial. Lancet. 2013;381(9869):805–16.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ganz PA, Greendale GA, Petersen L, Kahn B, Bower JE. Breast cancer in younger women: reproductive and late health effects of treatment. J Clin Oncol. 2003;21:4184–93.

    Article  PubMed  Google Scholar 

  10. Cluze C, Rey D, Huiart L, Bendiane MK, Bouhnik AD, Berenger C, Carrieri MP, Giorgi R. Adjuvant endocrine therapy with tamoxifen in young women with breast cancer: determinants of interruptions vary over time. Ann Oncol. 2012;23:882–90.

    Article  CAS  PubMed  Google Scholar 

  11. Howard-Anderson J, Ganz PA, Bower JE, Stanton AL. Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review. J Natl Cancer Inst. 2012;104:386–405.

    Article  PubMed  Google Scholar 

  12. Ben Charif A, Bouhnik AD, Rey D, Provansal M, Courbiere B, Spire B, Mancini J. Satisfaction with fertility- and sexuality-related information in young women with breast cancer – ELIPPSE40 cohort. BMC Cancer. 2015;15:572. doi:10.1186/s12885-015-1542-0.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Patricia Ganz, Julienne Bower, Annette Stanton. Special issues in younger women with breast cancer. Improving Outcomes for Breast Cancer Survivors. Volume 862 of the series Advances in Experimental Medicine and Biology, pp 9–21 (n.d.).

    Google Scholar 

  14. de Bock GH, van der Hage JA, Putter H, et al. Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: long-term results of European Organisation for Research and Treatment of Cancer studies. Eur J Cancer. 2006;42:351–6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Mount Sinai Beth Israel Hospital, 10 Union Square East, Suite 4E, New York, NY, 10003, USA

    Susan K. Boolbol MD & Sarah Cate MD

Authors
  1. Susan K. Boolbol MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sarah Cate MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Susan K. Boolbol MD .

Editor information

Editors and Affiliations

  1. Associate Professor of Surgery, Director Breast Care Center, Wake Forest School of Medicine, Winston-Salem, NC, USA

    Marissa Howard-McNatt

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this chapter

Cite this chapter

Boolbol, S.K., Cate, S. (2018). Breast Cancer Treatment in Young Women. In: Howard-McNatt, M. (eds) Changing Paradigms in the Management of Breast Cancer . Springer, Cham. https://doi.org/10.1007/978-3-319-60336-0_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-60336-0_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-60335-3

  • Online ISBN: 978-3-319-60336-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation