Skip to main content
SpringerLink
Log in
Book cover

Fluid, Electrolyte and Acid-Base Disorders pp 51–56Cite as

Diuretics

  • Chapter
  • First Online:

  • 3175 Accesses

Abstract

Diuretics promote Na+ and water excretion. Excretion of Na+ in the urine is called natriuresis, whereas diuresis refers to increased urine flow rate. In clinical medicine, two types of diuresis are recognized: solute diuresis and water diuresis. Solute diuresis results from a decrease in the renal tubular reabsorption of solute. Since water reabsorption follows solute reabsorption, inhibition of solute reabsorption generally diminishes water transport. However, water diuresis can be promoted without solute diuresis by drugs, which impair the action of antidiuretic hormone (ADH). Examples include ADH receptor blockers (vaptans) and lithium. This chapter reviews briefly the various groups of diuretics, their physiologic action, clinical use, and complications.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Suggested Reading

  1. Hoorn EJ, Wilcox CJ, Ellison DH. Diuretics. In: Skorecki K, et al., editors. Brenner & Rector’s the kidney. 10th ed. Philadelphia: Elsevier; 2016. p. 1702–33.

    Google Scholar 

  2. Reddy P, Mooradian AD. Diuretics: an update on the pharmacology and clinical uses. Am J Ther. 2009;16:74–85.

    Article  PubMed  Google Scholar 

  3. Seldin D, Giebisch G, editors. Diuretic agents. Clinical physiology and pharmacology. San Diego: Academic Press; 1997.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Nephrology and Hypertension, Rutgers New Jersey Medical, Newark, NJ, USA

    Alluru S. Reddi MD, PhD (Professor of Medicine, Chief)

Authors
  1. Alluru S. Reddi MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer Science+Business Media LLC

About this chapter

Cite this chapter

Reddi, A.S. (2018). Diuretics. In: Fluid, Electrolyte and Acid-Base Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-60167-0_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-60167-0_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-60166-3

  • Online ISBN: 978-3-319-60167-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation