Abstract
Hypophosphatemia is defined as serum [Pi] <2.5 mg/dL. Patients receiving mannitol develop pseudohypophosphatemia, which is caused by the binding of mannitol to the molybdate used to determine the serum [Pi]. Hypophosphatemia can be severe (serum [Pi] <1.0 mg/dL), moderate (serum [Pi] 1.0–1.9 mg/dL), or mild (serum [Pi] 2.0–2.5 mg/dL). Severe hypophosphatemia can occur in patients with prolonged use of antacids, such as aluminum hydroxide, magnesium hydroxide, or calcium carbonate or acetate. Moderate hypophosphatemia may be symptomatic or asymptomatic.
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Reddi, A.S. (2018). Disorders of Phosphate: Hypophosphatemia. In: Fluid, Electrolyte and Acid-Base Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-60167-0_21
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DOI: https://doi.org/10.1007/978-3-319-60167-0_21
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