Abstract
Measurement of urine Na+, Cl−, and K+ is rather common in hospitalized patients, and these urine electrolytes are useful in the diagnostic evaluation of volume status, hyponatremia, acute kidney injury (AKI), metabolic alkalosis, hypokalemia, and urine anion gap (urine net charge). A spot urine sample is generally adequate for determination of these electrolytes. In addition, urine creatinine is determined to calculate the fractional excretion of Na+, K+, or other electrolytes. Also, urine osmolality is helpful in the differential diagnosis of hyponatremia, polyuria, and AKI. Table 2.1 summarizes the clinical applications of urine electrolytes and osmolality.
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Kamel KS, Halperin ML. Intrarenal urea cycling leads to a higher rate of renal excretion of potassium: an hypothesis with clinical implications. Curr Opin Nephrol Hypertens. 2011;20:547–54.
Kamel KS, Ethier JH, Richardson RMA, et al. Urine electrolytes and osmolality: when and how to use them. Am J Nephrol. 1990;10:89–102.
Harrington JT, Cohen JJ. Measurement of urinary electrolytes-indications and limitations. N Engl J Med. 1975;293:1241–3.
Schrier RW. Diagnostic value of urinary sodium, chloride, urea, and flow. J Am Soc Nephrol. 2011;22:1610–3.
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Reddi, A.S. (2018). Interpretation of Urine Electrolytes and Osmolality. In: Fluid, Electrolyte and Acid-Base Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-60167-0_2
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DOI: https://doi.org/10.1007/978-3-319-60167-0_2
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