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Patient’s Guide: Diet and Lifestyle in Peptic Ulcer Disease

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Abstract

Diet may provide noxious agents which increase the pathogenicity of H. pylori, or protective agents that hamper their activity. The scope of this chapter is to elaborate on how dietary modulations and lifestyle habits can affect the course of H. pylori infection. We depict the role of several dietary components that may protect against the pathological consequences of H. pylori infection, and thus improve patient’s eradication therapy. Considering H. pylori as a strong and established risk factor of peptic ulcer, we also provide evidence between dietary exposure and the probability of tumor formation and/or prevention.

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Abbreviations

AA:

Ascorbic acid

bLF:

Bovine lactoferrin

CagA:

Cytotoxin-associated gene A

IDA:

Iron deficiency anemia

NO:

Nitric oxide

Nrf2:

Nuclear factor (erythroid-derived 2)-like 2

Th1:

T helper lymphocyte

WHO:

World Health Organization

References

  1. Woo HD, Park S, Oh K, Kim HJ, Shin HR, Moon HK, et al. Diet and cancer risk in the Korean population: a meta-analysis. Asian Pac J Cancer Prev. 2014;15(19):8509–19.

    Article  PubMed  Google Scholar 

  2. Chang YW, Jang JY, Kim YH, Kim JW, Shim JJ. Nonetheless, food such as broccoli sprouts, Manuka honey and omega-3 oil, independently or in combination attenuate inflammation and can have bacteriostatic activity. Gut Liver. 2015;9(4):486–93.

    Article  PubMed  Google Scholar 

  3. Demirci H, İlikhan SU, Öztürk K, Üstündağ Y, Kurt Ö, Bilici M, et al. Influence of vitamin C and E supplementation on the eradication rates of triple and quadruple eradication regimens for Helicobacter pylori infection. Turk J Gastroenterol. 2015;26:456–60.

    Article  PubMed  Google Scholar 

  4. Aditi A, Graham DY. Vitamin C, gastritis, and gastric disease: a historical review and update. Dig Dis Sci. 2012;57(10):2504–15.

    Article  CAS  PubMed  Google Scholar 

  5. Kaboli SA, Zojaji H, Mirsattari D, Talaie R, Derakhshan F, Zali MR, et al. Effect of addition of vitamin C to clarithromycin-amoxicillin-omeprazol triple regimen on Helicobacter pylori eradication. Acta Gastroenterol Belg. 2009;72(2):222–4.

    PubMed  Google Scholar 

  6. Kamiji MM, de Oliveira RB. Effect of vitamin C administration on gastric colonization by Helicobacter pylori. Arq Gastroenterol. 2005;42(3):167–72.

    Article  PubMed  Google Scholar 

  7. Fox JG, Wang TC. Dietary factors modulate helicobacter-associated gastric cancer in rodent models. Toxicol Pathol. 2014;42(1):162–81.

    Article  PubMed  Google Scholar 

  8. Lee C-W, Wang X-D, Chien K-L, Ge Z, Rickman BH, Rogers AB, et al. Vitamin C supplementation does not protect L-gulono-γ-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy. Int J Cancer. 2007;122(5):1068–76.

    Article  Google Scholar 

  9. Chuang C-H, Sheu B-S, Kao A-W, Cheng H-C, Huang A-H, Yang H-B, et al. Adjuvant effect of vitamin C on omeprazole-amoxicillin-clarithromycin triple therapy for Helicobacter pylori eradication. Hepato-Gastroenterology. 2007;54(73):320–4.

    CAS  PubMed  Google Scholar 

  10. Zojaji H, Talaie R, Mirsattari D, Haghazali M, Molaei M, Mohsenian N, et al. The efficacy of Helicobacter pylori eradication regimen with and without vitamin C supplementation. Dig Liver Dis. 2009;41(9):644–7.

    Article  CAS  PubMed  Google Scholar 

  11. Sezikli M, Çetinkaya ZA, Güzelbulut F, Yeşil A, Coşgun S, Kurdaş OÖ. Supplementing vitamins C and E to standard triple therapy for the eradication of Helicobacter pylori. J Clin Pharm Ther. 2012;37(3):282–5.

    Article  CAS  PubMed  Google Scholar 

  12. Everett SM, Drake IM, White KLM, Mapstone NP, Chalmers DM, Schorah CJ, et al. Antioxidant vitamin supplements do not reduce reactive oxygen species activity in Helicobacter pylori gastritis in the short term. Br J Nutr. 2002;87(1):3.

    Article  CAS  PubMed  Google Scholar 

  13. Li G1, Li L, Yu C, Chen L. Effect of vitamins C and E supplementation on Helicobacter pylori eradication: a meta-analysis. Br J Nutr. 2011;106(11):1632–7.

    Google Scholar 

  14. Hamatani R, Otsu M, Chikamoto H, Akioka Y, Hattori M. Plasma homocysteine and folate levels and dietary folate intake in adolescents and young adults who underwent kidney transplantation during childhood. Clin Exp Nephrol. 2014;18(1):151–6.

    Article  CAS  PubMed  Google Scholar 

  15. Rasool S, Abid S, Iqbal MP, Mehboobali N, Haider G, Jafri W. Relationship between vitamin B 12, folate and homocysteine levels and H. Pylori infection in patients with functional dyspepsia: a cross-section study. BMC Res Notes. 2012;5:206.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Javadi L, Pourghassem Gargari B, Salekzamani S, Yousefzadeh R. Folate and homocysteine levels and their association with dietary intakes in Iranian patients infected with Helicobacter pylori: a case-control study. Acta Med Iran. 2015;53(3):162–7.

    PubMed  Google Scholar 

  17. Itou S, Goto Y, Kondo T, Nishio K, Kawai S, Ishida Y, et al. No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese. Int J Med Sci. 2007;4(2):98–104.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Jung SW, Lee SW. The antibacterial effect of fatty acids on Helicobacter pylori infection. Korean J Intern Med. 2016;31(1):30–5.

    Article  PubMed  Google Scholar 

  19. Thamphiwatana S, Gao W, Obonyo M, Zhang L. In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation. Proc Natl Acad Sci. 2014;111(49):17600–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Khandouzi N, Shidfar F, Agah S, Hosseini AF, Dehnad A. Comparison of the effects of eicosapentaenoic acid and docosahexaenoic acid on the eradication of Helicobacter pylori infection, serum inflammatory factors and total antioxidant capacity. Iran J Pharm Res. 2015;14(1):149–57.

    CAS  PubMed  PubMed Central  Google Scholar 

  21. Keenan JI, Salm N, Wallace AJ, Hampton MB. Using food to reduce H. pylori-associated inflammation. Phytother Res. 2012;26(11):1620–5.

    Article  CAS  PubMed  Google Scholar 

  22. De Reuse H, Vinella D, Cavazza C, Pignol D, Danielli A. Common themes and unique proteins for the uptake and trafficking of nickel, a metal essential for the virulence of Helicobacter pylori (Mini Review Article). Front Cell Infect Microbiol. 2013;3:94.

    Google Scholar 

  23. Benoit SL, Miller EF, Maier RJ. Helicobacter pylori stores nickel to aid its host colonization. Infect Immun. 2013;81(2):580–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Campanale M, Nucera E, Ojetti V, Cesario V, Di Rienzo TA, D’Angelo G, et al. Nickel free-diet enhances the Helicobacter pylori eradication rate: a pilot study. Dig Dis Sci. 2014;59(8):1851–5.

    Article  CAS  PubMed  Google Scholar 

  25. Beckett AC, Piazuelo MB, Noto JM, Peek RM, Washington MK, Algood HMS, et al. Dietary composition influences incidence of Helicobacter pylori-induced iron deficiency anemia and gastric ulceration. Blanke SR, editor. Infect Immun. 2016;84(12):3338–49.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Annibale B, Capurso G, Lahner E, Passi S, Ricci R, Maggio F, et al. Concomitant alterations in intragastric pH and ascorbic acid concentration in patients with Helicobacter pylori gastritis and associated iron deficiency anaemia. Gut. 2003;52:496–501.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Malik R, Guleria K, Kaur I, Sikka M, Radhakrishnan G. Effect of Helicobacter pylori eradication therapy in iron deficiency anaemia of pregnancy - a pilot study. Indian J Med Res. 2011;134(2):224–31.

    PubMed  PubMed Central  Google Scholar 

  28. Huang X, Qu X, Yan W, Huang Y, Cai M, Hu B, et al. Iron deficiency anaemia can be improved after eradication of Helicobacter pylori. Postgrad Med J. 2010;86(1015):272–8.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Hudak L, Jaraisy A, Haj S, Muhsen K. An updated systematic review and meta-analysis on the association between Helicobacter pylori infection and iron deficiency anemia. Helicobacter. 2017;22(1):e12330.

    Article  Google Scholar 

  30. Chey WD, Leontiadis GI, Howden CW, Moss SF. ACG clinical guideline: treatment of Helicobacter pylori infection. Am J Gastroenterol. 2017;112(2):212–39. Available from: http://www.nature.com/doifinder/10.1038/ajg.2016.563

    Article  PubMed  Google Scholar 

  31. Vomero ND, Colpo E. Nutritional care in peptic ulcer. ABCD Arq Bras Cir Dig. 2014;27(4):298–302.

    Article  PubMed  Google Scholar 

  32. Jakszyn P, Agudo A, Lujan-Barroso L, Bueno-De-Mesquita HB, Jenab M, Navarro C, et al. Dietary intake of heme iron and risk of gastric cancer in the European prospective investigation into cancer and nutrition study. Int J Cancer. 2012;130(11):2654–63.

    Article  CAS  PubMed  Google Scholar 

  33. Gonzallez CA, Jakszyn P, Pera G, Agudo A, Bingham S, Palli D, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European prospective investigation into cancer and nutrition (EPIC). J Natl Cancer Inst. 2006;98(5):345–54.

    Article  Google Scholar 

  34. Mendez MA, Pera G, Agudo A, Bas Bueno-de-Mesquita H, Palli D, Boeing H, et al. Cereal fiber intake may reduce risk of gastric adenocarcinomas: the EPIC-EURGAST study. Int J Cancer. 2007;121(7):1618–23.

    Article  CAS  Google Scholar 

  35. Liu C, Russell RM. Nutrition and gastric cancer risk: an update. Nutr Rev. 2008;66(5):237–49.

    Article  PubMed  Google Scholar 

  36. Takeuchi H, Trang VT, Morimoto N, Nishida Y, Matsumura Y, Sugiura T. Natural products and food components with anti-Helicobacter pylori activities. World J Gastroenterol. 2014;20(27):8971–8.

    PubMed  PubMed Central  Google Scholar 

  37. Di Mario F, Aragona G, Bò ND, Ingegnoli A, Cavestro GM, Moussa AM, et al. Use of lactoferrin for Helicobacter pylori eradication. Preliminary results. J Clin Gastroenterol. 2017;36(5):396–8.

    Article  Google Scholar 

  38. di Mario F, Aragona G, Dal Bo N, Cavallaro L, Marcon V, Olivieri P, et al. Bovine lactoferrin for Helicobacter pylori eradication: an open, randomized, multicentre study. Aliment Pharmacol Ther. 2006;23(8):1235–40.

    Article  PubMed  Google Scholar 

  39. Yamazaki N, Yamauchi K, Kawase K, Hayasawa H, Nakao K, Imoto I. Antibacterial effects of lactoferrin and a pepsin-generated lactoferrin peptide against Helicobacter pylori in vitro. J Infect Chemother. 1997;3(2):85–9.

    Article  CAS  Google Scholar 

  40. Kato S, Tsukamoto T, Mizoshita T, Tanaka H, Kumagai T, Ota H, et al. High salt diets dose-dependently promote gastric chemical carcinogenesis in Helicobacter pylori-infected Mongolian gerbils associated with a shift in mucin production from glandular to surface mucous cells. Int J Cancer. 2006;119(7):1558–66.

    Article  CAS  PubMed  Google Scholar 

  41. Gaddy JA, Radin JN, Loh JT, Zhang F, Kay Washington M, Peek RM, et al. High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Infect Immun. 2013;81(6):2258–67.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Bergin IL, Sheppard BJ, Fox JG. Helicobacter pylori infection and high dietary salt independently induce atrophic gastritis and intestinal metaplasia in commercially available outbred Mongolian gerbils. Dig Dis Sci. 2003;48(3):475–85.

    Article  CAS  PubMed  Google Scholar 

  43. Lin S, Li Y, Leung K, Huang C, Wang X. Salt processed food and gastric cancer in a Chinese population. Asian Pac J Cancer Prev. 2014;15:5293–8.

    Article  PubMed  Google Scholar 

  44. Chikan NA, Shabir N, Shaffi S, Mir MR, Trupti N. N-nitrosodimethylamine in the Kashmiri diet and possible roles in the high incidence of gastrointestinal cancers (Commentary). Asian Pac J Cancer Prev. 2012;13:1077–9.

    Article  PubMed  Google Scholar 

  45. Tsugane S. Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence. Cancer Sci. 2005;96(1):1–6.

    Article  CAS  PubMed  Google Scholar 

  46. Jakszyn P, Bingham S, Pera G, Agudo A, Luben R, Welch A, et al. Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European prospective investigation into cancer and nutrition (EPIC-EURGAST) study. Carcinogenesis. 2006;27(7):1497–501.

    Article  CAS  PubMed  Google Scholar 

  47. Härtl G. WHO issues new guidance on dietary salt and potassium. Retrieved from: http://www.who.int/mediacentre/news/notes/2013/salt_potassium_20130131/en/. 2013.

  48. Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, et al. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans. Cancer Prev Res. 2009;2(4):353–60.

    Article  CAS  Google Scholar 

  49. Moon JK, Kim JR, Ahn YJ, Shibamoto T. Analysis and anti-helicobacter activity of sulforaphane and related compounds present in broccoli (Brassica oleracea L.) sprouts. J Agric Food Chem. 2010;58(11):6672–7.

    Article  CAS  PubMed  Google Scholar 

  50. Bahadoran Z, Mirmiran P, Yeganeh MZ, Hosseinpanah F, Zojaji H, Azizi F. Complementary and alternative medicinal effects of broccoli sprouts powder on Helicobacter pylori eradication rate in type 2 diabetic patients: a randomized clinical trial. J Funct Foods. 2014;7(1):390–7.

    Article  CAS  Google Scholar 

  51. Marx W. Tracking historical papers and their citations. Eur Sci Ed. 2012;38(2):35–7.

    Google Scholar 

  52. Brown JC, Jiang X. Activities of muscadine grape skin and polyphenolic constituents against Helicobacter pylori. J Appl Microbiol. 2013;114(4):982–91.

    Article  CAS  PubMed  Google Scholar 

  53. Gotteland M, Andrews M, Toledo M, Muñoz L, Caceres P, Anziani A, et al. Modulation of Helicobacter pylori colonization with cranberry juice and Lactobacillus johnsonii La1 in children. Nutrition. 2008;24(5):421–6.

    Article  PubMed  Google Scholar 

  54. Chua C-S, Yang K-C, Chen J-H, Liu Y-H, Hsu Y-H, Lee H-C, et al. The efficacy of blueberry and grape seed extract combination on triple therapy for Helicobacter pylori eradication: a randomised controlled trial. Int J Food Sci Nutr. 2016;67(2):177–83.

    Article  CAS  PubMed  Google Scholar 

  55. Chatterjee A, Yasmin T, Bagchi D, Stohs SJ. Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin. Mol Cell Biochem. 2004;265(1–2):19–26.

    Article  CAS  PubMed  Google Scholar 

  56. Friedman M. Antibacterial, antiviral, and antifungal properties of wines and winery byproducts in relation to their flavonoid content. J Agric Food Chem. 2014;62(26):6025–42.

    Article  CAS  PubMed  Google Scholar 

  57. Ali Mard S, Khadem Haghighian H, Sebghatulahi V, Ahmadi B. Dietary factors in relation to Helicobacter pylori infection. Gastroenterol Res Pract. 2014;2014:1–5.

    Article  Google Scholar 

  58. Manyi-Loh CE, Clarke AM, Mkwetshana NF, Ndip RN. Treatment of Helicobacter pylori infections: mitigating factors and prospective natural remedies. Afr J Biotechnol. 2010;9(14):2032–42.

    CAS  Google Scholar 

  59. Cui K, Lu W, Zhu L, Shen X, Huang J. Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity. Biochem Biophys Res Commun. 2013;435:289–94.

    Article  CAS  PubMed  Google Scholar 

  60. Sullivan A, Nord CE. Probiotics and gastrointestinal diseases. J Intern Med. 2005;257(1):78–92.

    Article  CAS  PubMed  Google Scholar 

  61. Johnson-Henry KC, Mitchell DJ, Avitzur Y, Galindo-Mata E, Jones NL, Sherman PM. Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice. Dig Dis Sci. 2004;49(7–8):1095–102.

    Article  PubMed  Google Scholar 

  62. Sgouras DN, Panayotopoulou EG, Martinez-Gonzalez B, Petraki K, Michopoulos S, Mentis A. Lactobacillus johnsonii La1 attenuates Helicobacter pylori-associated gastritis and reduces levels of proinflammatory chemokines in C57BL/6 mice. Clin Diagn Lab Immunol. 2005;12(12):1378–86.

    CAS  PubMed  PubMed Central  Google Scholar 

  63. de Bortoli N, Leonardi G, Ciancia E, Merlo A, Bellini M, Costa F, et al. Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics. Am J Gastroenterol. 2007;102(5):951–6.

    Article  PubMed  Google Scholar 

  64. Tolone S, Pellino V, Vitaliti G, Lanzafame A, Tolone C. Evaluation of Helicobacter Pylori eradication in pediatric patients by triple therapy plus lactoferrin and probiotics compared to triple therapy alone. Ital J Pediatr. 2012;38(1):63.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Dang Y, Reinhardt JD, Zhou X, Zhang G. The effect of probiotics supplementation on Helicobacter pylori eradication rates and side effects during eradication therapy: a meta-analysis. Cardona P-J, editor. PLoS One. 2014;9(11):e111030.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Homan M, Orel R. Are probiotics useful in Helicobacter pylori eradication? World J Gastroenterol. 2015;21(3):10644–53.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  67. Szajewska H, Horvath A, Piwowarczyk A. Meta-analysis: the effects of Saccharomyces boulardii supplementation on Helicobacter pylori eradication rates and side effects during treatment. Aliment Pharmacol Ther. 2010;32(9):1069–79.

    Article  CAS  PubMed  Google Scholar 

  68. Song MJ, Park D II, Park JH, Kim HJ, Cho YK, Sohn C II, et al. The effect of probiotics and mucoprotective agents on PPI- based triple therapy for eradication of Helicobacter pylori. Helicobacter. 2010;15:206–13.

    Article  CAS  PubMed  Google Scholar 

  69. Wilhelm SM, Johnson JL, Kale-Pradhan PB. Treating bugs with bugs: the role of probiotics as adjunctive therapy for Helicobacter pylori. Ann Pharmacother. 2011;45(7–8):960–6.

    Article  PubMed  Google Scholar 

  70. Sýkora J, Valecková K, Amlerová J, Siala K, Dedek P, Watkins S, et al. Effects of a specially designed fermented milk product containing probiotic Lactobacillus casei DN-114 001 and the eradication of H. pylori in children: a prospective randomized double-blind study. J Clin Gastroenterol. 2005;39(8):692–8.

    Article  PubMed  Google Scholar 

  71. Ojetti V, Bruno G, Ainora ME, Gigante G, Rizzo G, Roccarina D, et al. Impact of Lactobacillus reuteri supplementation on anti-Helicobacter pylori levofloxacin-based second-line therapy. Gastroenterol Res Pract. 2012;2012:1–6.

    Article  Google Scholar 

  72. Emara MH, Mohamed SY, Abdel-Aziz HR. Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial. Ther Adv Gastroenterol. 2014;7(1):4–13.

    Article  Google Scholar 

  73. Chenoll E, Casinos B, Bataller E, Astals P, Echevarría J, Iglesias JR, et al. Novel probiotic Bifidobacterium bifidum CECT 7366 strain active against the pathogenic bacterium Helicobacter pylori. Appl Environ Microbiol. 2011;77(4):1335–43.

    Article  CAS  PubMed  Google Scholar 

  74. de Vrese M, Kristen H, Rautenberg P, Laue C, Schrezenmeir J. Probiotic lactobacilli and bifidobacteria in a fermented milk product with added fruit preparation reduce antibiotic associated diarrhea and Helicobacter pylori activity. J Dairy Res. 2011;78(4):396–403.

    Article  PubMed  Google Scholar 

  75. Khodadad A, Farahmand F, Najafi M, et al. Probiotics for the treatment of pediatric Helicobacter Pylori infection: a randomized double blind clinical trial. Iran J Pediatr. 2013;23(1):79–84.

    PubMed Central  Google Scholar 

  76. Szajewska H, Albrecht P, Topczewska-Cabanek A. Randomized, double-blind, placebo-controlled trial: effect of lactobacillus GG supplementation on Helicobacter pylori eradication rates and side effects during treatment in children. J Pediatr Gastroenterol Nutr. 2009;48(4):431–6.

    Article  CAS  PubMed  Google Scholar 

  77. Brenner H, Rothenbacher D, Bode G, Adler G. Relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection: cross sectional study. BMJ. 1997;315(7121):1489–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  78. Murray LJ, Lane AJ, Harvey IM, Donovan JL, Nair P, Harvey RF. Inverse relationship between alcohol consumption and active Helicobacter pylori infection: the Bristol Helicobacter project. Am J Gastroenterol. 2002;97(11):2750–5.

    Article  PubMed  Google Scholar 

  79. Brenner H, Bode G, Adler G, Hoffmeister A, Koenig W, Rothenbacher D. Alcohol as a gastric disinfectant? The complex relationship between alcohol consumption and current Helicobacter pylori infection. Epidemiology. 2001;12(2):209–14.

    Article  CAS  PubMed  Google Scholar 

  80. Moy KA, Fan Y, Wang R, Gao Y-T, Yu MC, Yuan J-M. Alcohol and tobacco use in relation to gastric cancer: a prospective study of men in Shanghai, China. Cancer Epidemiol Biomark Prev. 2010;19(9):2287–97.

    Article  CAS  Google Scholar 

  81. Vinagre RMDF, Vilar e Silva A, Fecury AA, Martins LC. Role of Helicobacter pylori infection and lifestyle habits in the development of gastroduodenal diseases in a population from the Brazilian Amazon. Arq Gastroenterol. 2013;50(3):170–4.

    Article  PubMed  Google Scholar 

  82. Lee YY, Derakhshan MH. Environmental and lifestyle risk factors of gastric cancer. Arch Iran Med. 2013;16(6):358–65.

    PubMed  Google Scholar 

  83. Buckland G, Travier N, Huerta JM, Bueno-de-Mesquita HBA, Siersema PD, Skeie G, et al. Healthy lifestyle index and risk of gastric adenocarcinoma in the EPIC cohort study. Int J Cancer. 2015;137(3):598–606.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

The authors are supported by the Medical University of Lodz [#502-03/1-156-04/502-14-299 to PM, #502-03/1-156-04/502-14-239 to AW] and the National Science Centre [#UMO-2016/21/N/NZ5/01932 to PM]. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

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Mosińska, P., Wasilewski, A. (2017). Patient’s Guide: Diet and Lifestyle in Peptic Ulcer Disease. In: Fichna, J. (eds) Introduction to Gastrointestinal Diseases Vol. 2. Springer, Cham. https://doi.org/10.1007/978-3-319-59885-7_7

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