Risk Mediation in Association Rules

The Case of Decision Support in Medication Review
  • Michiel C. MeulendijkEmail author
  • Marco R. Spruit
  • Sjaak Brinkkemper
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 10259)


We propose a model for the incorporation of risk in association rule application. We validate this model using data gathered in a randomized controlled trial from a recommender system for medication reviews in primary care. The model’s outcomes are found to have predictive value when tested against decisions made by physicians on 261 patients’ health records.


Association rules Decision support Risk management 


  1. 1.
    Meulendijk, M., et al.: STRIPA: A Rule-Based Decision Support System for Medication Reviews in Primary Care. In: Proceedings of ECIS 2015, Münster, Germany (2015)Google Scholar
  2. 2.
    Meulendijk, M., et al.: Computerized decision support improves medication review effectiveness: an experiment evaluating the STRIP Assistant’s usability. Drugs Aging 32(6), 495–503 (2015)CrossRefGoogle Scholar
  3. 3.
    Meulendijk, M., et al.: Efficiency of clinical decision support systems improves with experience. J. Med. Syst. 40(4), 76–82 (2016)CrossRefGoogle Scholar
  4. 4.
    Meulendijk, M., Spruit, M., Brinkkemper, S.: Risk Mediation in Association Rules: Application Examples, Utrecht University, UU-CS-2017-004 (2017)Google Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Michiel C. Meulendijk
    • 1
    Email author
  • Marco R. Spruit
    • 2
  • Sjaak Brinkkemper
    • 2
  1. 1.Department of Public Health and Primary CareLeiden University Medical CenterLeidenThe Netherlands
  2. 2.Department of Information and Computing SciencesUtrecht UniversityUtrechtThe Netherlands

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