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Pyogenic Liver Abscess

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Abdominal Sepsis

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

Abstract

A hepatic abscess is a suppurated cavity caused by the invasion and multiplication of microorganisms within the liver parenchyma [1]. It can be bacterial (pyogenic), parasitic (amebic), mixed (pyogenic superinfection of parasitic abscess), or rarely fungal. Adult pyogenic liver abscess (PLA) is a major hepatobiliary infection with mortality of up to 46% [2–4]. The recent improvement in mortality can be attributed to improved understanding of sepsis with advances in interventional radiology and critical care. The cornerstone of PLA treatment remains antibiotic therapy with percutaneous drainage/aspiration. The first significant study on PLAs was performed by Ochsner in 1938, and he reported association with young men, portal pyemia, and 77% mortality [5].

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Author information

Authors and Affiliations

  1. Tan Tock Seng Hospital, Singapore, 308433, Singapore

    Yeo Danson FRCS, Tan Ming Yuan FRCS & Vishal G. Shelat FRCS, FEBS(HPB Surg)

  2. Yong Loo Lin School of Medicine, Singapore, Singapore

    Yeo Danson FRCS, Tan Ming Yuan FRCS & Vishal G. Shelat FRCS, FEBS(HPB Surg)

Authors
  1. Yeo Danson FRCS
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  2. Tan Ming Yuan FRCS
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  3. Vishal G. Shelat FRCS, FEBS(HPB Surg)
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Corresponding author

Correspondence to Vishal G. Shelat FRCS, FEBS(HPB Surg) .

Editor information

Editors and Affiliations

  1. Department of Surgery, Macerata Hospital, Macerata, Italy

    Massimo Sartelli

  2. University of Udine, Infectious Diseases Division , Udine, Italy

    Matteo Bassetti

  3. St James's University Hospital, Trinity Centre for Health Sciences , Dublin, Ireland

    Ignacio Martin-Loeches

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Danson, Y., Yuan, T.M., Shelat, V.G. (2018). Pyogenic Liver Abscess. In: Sartelli, M., Bassetti, M., Martin-Loeches, I. (eds) Abdominal Sepsis. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-319-59704-1_8

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  • DOI: https://doi.org/10.1007/978-3-319-59704-1_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59703-4

  • Online ISBN: 978-3-319-59704-1

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