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High-Risk Patients and Prognostic Factors for Abdominal Sepsis

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Abdominal Sepsis

Abstract

In general, patients in high risk are those who have elevated chances of acquiring and failing treatment. Many factors are associated with these conditions and need to be identified quickly as the effective management of this specific sick population requires early and prompt treatment.

Knowledge of the patient’s risk is essential to begin treatment as soon as possible with the most appropriate strategy.

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References

  1. Marshall JC. Intra-abdominal infections. Microbes Infect. 2004;6(11):1015–25.

    Article  PubMed  Google Scholar 

  2. Blot S, De Waele JJ. Critical issues in the clinical management of complicated intra-abdominal infections. Drugs. 2005;65(12):1611–20.

    Article  PubMed  Google Scholar 

  3. Sartelli M. A focus on intra-abdominal infections. World J Emerg Surg. 2010;5:9.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Das K, Ozdogan M, Karateke F, Uzun AS, Sozen S, Ozdas S. Comparison of APACHE II, P-POSSUM and SAPS II scoring systems in patients underwent planned laparotomies due to secondary peritonitis. Ann Ital Chir. 2014;85(1):16–21.

    PubMed  Google Scholar 

  5. Koperna T, Semmler D, Marian F. Risk stratification in emergency surgical patients: is the APACHE II score a reliable marker of physiological impairment? Arch Surg. 2001;136(1):55–9.

    Article  CAS  PubMed  Google Scholar 

  6. Sartelli M, Abu-Zidan FM, Catena F, Griffiths EA, Di Saverio S, Coimbra R, et al. Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS study). World J Emerg Surg. 2015;10:61.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Deitch EA. Gut-origin sepsis: evolution of a concept. Surgeon. 2012;10(6):350–6.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Solomkin JS, Mazuski JE, Bradley JS, Rodvold KA, Goldstein EJC, Baron EJ, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis. 2010;50(2):133–64.

    Article  PubMed  Google Scholar 

  9. Garcia-Vazquez E, Albendin H, Hernandez-Torres A, Canteras M, Yague G, Ruiz J, et al. Study of a cohort of patients with Enterococcus spp. Bacteraemia. Risk factors associated to high-level resistance to aminoglycosides. Revi Esp Quimioter. 2013;26(3):203–13.

    Google Scholar 

  10. Peralta G, Lamelo M, Alvarez-Garcia P, Velasco M, Delgado A, Horcajada JP, et al. Impact of empirical treatment in extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. bacteremia. A multicentric cohort study. BMC Infect Dis. 2012;12:245.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Bassetti M, Righi E, Ansaldi F, Merelli M, Scarparo C, Antonelli M, et al. A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality. Intensive Care Med. 2015;41(9):1601–10.

    Article  PubMed  Google Scholar 

  12. Benjamin E, Siboni S, Haltmeier T, Inaba K, Lam L, Demetriades D. Deep organ space infection after emergency bowel resection and anastomosis: the anatomic site does not matter. J Trauma Acute Care Surg. 2015;79(5):805–11.

    Article  PubMed  Google Scholar 

  13. Hernandez-Palazon J, Fuentes-Garcia D, Burguillos-Lopez S, Domenech-Asensi P, Sansano-Sanchez TV, Acosta-Villegas F. Analysis of organ failure and mortality in sepsis due to secondary peritonitis. Med Intensiva. 2013;37(7):461–7.

    Article  CAS  PubMed  Google Scholar 

  14. NICE [National Institute for Health and Care Excellence]. Sepsis: recognition, diagnosis and early management. NICE guideline, 13 July 2016. Nice.org.uk/guidance/ng51. Accessed Sept 2016.

  15. Hecker A, Uhle F, Schwandner T, Padberg W, Weigand MA. Diagnostics, therapy and outcome prediction in abdominal sepsis: current standards and future perspectives. Langenbecks Arch Surg. 2014;399(1):11–22.

    Article  CAS  PubMed  Google Scholar 

  16. Tellor B, Skrupky LP, Symons W, High E, Micek ST, Mazuski JE. Inadequate source control and inappropriate antibiotics are key determinants of mortality in patients with intra-abdominal sepsis and associated bacteremia. Surg Infect. 2015;16(6):785–93.

    Article  Google Scholar 

  17. Boncagni F, Francolini R, Nataloni S, Skrami E, Gesuita R, Donati A, et al. Epidemiology and clinical outcome of healthcare-associated infections: a 4-year experience of an Italian ICU. Minerva Anestesiol. 2015;81(7):765–75.

    CAS  PubMed  Google Scholar 

  18. Soriano G, Castellote J, Alvarez C, et al. Secondary bacterial peritonitis in cirrhosis: a retrospective study of clinical and analytical characteristics, diagnosis and management. J Hepatol. 2010;52(1):39–44.

    Article  PubMed  Google Scholar 

  19. Colizza S, Rossi S. Antibiotic prophylaxis and treatment of surgical abdominal sepsis. J Chemother. 2001;13 Spec No 1(1):193–201.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Gustavo P. Fraga M.D., Ph.D. .

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Pereira, B.M., Fraga, G.P. (2018). High-Risk Patients and Prognostic Factors for Abdominal Sepsis. In: Sartelli, M., Bassetti, M., Martin-Loeches, I. (eds) Abdominal Sepsis. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-319-59704-1_4

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  • DOI: https://doi.org/10.1007/978-3-319-59704-1_4

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