Abstract
Antiphospholipid syndrome (APS) is a disorder that is characterized by the presence of antibodies to phospholipid-binding proteins and several other clinical findings. This syndrome results in frequent thromboses and a high level of peripartum morbidity. Women who are pregnant or are considering pregnancy should be carefully evaluated and placed on the appropriate thrombophylaxis for the duration of the pregnancy. The most important consideration for anesthesia providers is the management of thrombophylaxis during the laboring period. Neuraxial anesthesia should be managed carefully with the ASRA (American Society of Regional Anesthesia) anticoagulation guidelines, and patients should be carefully monitored for both bleeding and significant thromboses during the course of labor. Postpartum considerations include the potential development of life-threatening thrombosis and decision about long-term anticoagulation.
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Abbreviations
- APS:
-
Antiphospholipid syndrome
- ASRA:
-
American Society of Regional Anesthesia
- LMWH:
-
Low molecular weight heparin
- SLE:
-
Systemic lupus erythematosus
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Paek, J., Chandrasekhar, S. (2018). Antiphospholipid Syndrome. In: Mankowitz, S. (eds) Consults in Obstetric Anesthesiology. Springer, Cham. https://doi.org/10.1007/978-3-319-59680-8_9
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DOI: https://doi.org/10.1007/978-3-319-59680-8_9
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