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Transcatheter Mitral Valve Implantation

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Percutaneous Treatment of Left Side Cardiac Valves

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Abstract

Mitral regurgitation (MR) is the most common cardiac valve pathology in Western countries, with an estimated prevalence of moderate and severe MR in the USA of 2–2.5 million. Though surgical valve repair and replacement are the current gold standard treatment for significant MR, surgery can be associated with significant morbidity and even mortality. This fact and the desire for less invasive approaches have led to the development of a variety of percutaneous approaches to treat MR. New transcatheter mitral repair technologies, such as the MitraClip™ system and other transcatheter devices using the concepts of annuloplasty, chordal implantation, or left ventricular (LV) remodeling, may offer a less invasive alternative to conventional surgery. However, these approaches have their own drawbacks, including failure to eliminate MR completely. Transcatheter mitral valve implantation (TMVI), in contrast, has the potential to reduce MR to a similar extent as that achieved with surgery, with the potential for reducing invasiveness and procedural risk. The first-in-human percutaneous TMVI for native mitral valve regurgitation was performed in 2012. Since then, several medical device companies have been attempting to bring suitable transcatheter valves to the market. This chapter aims to introduce the transcatheter MV implantation (TMVI) devices currently being evaluated in human trials.

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Authors and Affiliations

  1. Center for Heart Valve Innovation, St Paul’s Hospital, Vancouver, BC, Canada

    Adrian Attinger-Toller, Anson Cheung & John G. Webb

Authors
  1. Adrian Attinger-Toller
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  2. Anson Cheung
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  3. John G. Webb
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Corresponding author

Correspondence to John G. Webb .

Editor information

Editors and Affiliations

  1. Ferrarotto Hospital, University of Catania, Catania, Italy

    Corrado Tamburino

  2. Ferrarotto Hospital, University of Catania, Catania, Italy

    Marco Barbanti

  3. Ferrarotto Hospital, University of Catania, Catania, Italy

    Davide Capodanno

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Attinger-Toller, A., Cheung, A., Webb, J.G. (2018). Transcatheter Mitral Valve Implantation. In: Tamburino, C., Barbanti, M., Capodanno, D. (eds) Percutaneous Treatment of Left Side Cardiac Valves. Springer, Cham. https://doi.org/10.1007/978-3-319-59620-4_11

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  • DOI: https://doi.org/10.1007/978-3-319-59620-4_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59619-8

  • Online ISBN: 978-3-319-59620-4

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