Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Robust Model-Based Registration of Cardiac MR Images for T1 and ECV Mapping

  • Conference paper
  • First Online:
Functional Imaging and Modelling of the Heart (FIMH 2017)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 10263))

  • 1755 Accesses

Abstract

Quantification of myocardial T1 and extra cellular volume (ECV) in cardiac MRI provides relevant diagnostic information about myocardial structure. However, since these maps are pixel-wise calculated from two sequences of T1-weighted images, they are frequently disturbed by motion artifacts originating from e.g. patient motion, failure in breath-hold or cardiac motion. We propose a new non-rigid registration framework combining a robust data-driven initialization with a model-based refinement. The data-driven algorithm finds an optimal registration sequence of images for calculation of an initial T1 map. The registration is subsequently refined by exploiting the exponential relaxation model of T1. Validation using 20 in-vivo data sets showed a decrease in mean boundary error and an increase in global Dice coefficient.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Schelbert, E.B., Messroghli, D.R.: State of the art: clinical applications of cardiac T1 mapping. Radiology 278(3), 658–676 (2016)

    Article  Google Scholar 

  2. Messroghli, D.R., Radjenovic, A., Kozerke, S., Higgins, D.M., Sivananthan, M.U., Ridgway, J.P.: Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn. Reson. Med. 52, 141–146 (2004)

    Article  Google Scholar 

  3. Kellman, P., Arai, A.E., Xue, H.: T1 and extracellular volume mapping in the heart: estimation of error maps and the influence of noise on precision. J. Cardiovasc. Magn. Reson. 15(1), 56 (2013)

    Article  Google Scholar 

  4. Xue, H., Shah, S., Greiser, A., Guetter, C., Littmann, A., Jolly, P.-P., Arai, A.E., Zuehlsdorff, S., Guehring, J., Kellman, P.: Motion correction for myocardial T1 mapping using image registration with synthetic image estimation. Magn. Reson. Med. 57, 1644–1655 (2012)

    Article  Google Scholar 

  5. Roujol, S., Foppa, M., Weingartner, S., Manning, W.J., Nezefat, R.: Adaptive registration of varying contrast-weighted images for improved tissue characterization (ARCTIC): Application to T1 mapping. Magn. Reson. Med. 73, 1469–1482 (2015)

    Article  Google Scholar 

  6. Huizinga, W., Poot, D., Guyader, J.-M., Klaassen, R., van Coolen, B., Kranenburg, M., van Geuns, R., Uitterdijk, A., Polfliet, M., Vandemeulebroucke, J., Leemans, A., Niessen, W., Klein, S.: PCA-based groupwise image registration for quantitative MRI. Med. Image Anal. 29, 65–78 (2016)

    Article  Google Scholar 

  7. Van De Giessen, M., Tao, Q., Van Der Geest, R.J., Lelieveldt, B.P.F.: Model-based alignment of look-locker MRI sequences for calibrated myocardial scar tissue quantification. In: 10th IEEE International Symposium on Biomedical Imaging From Nano to Macro, pp. 1038–1041 (2013)

    Google Scholar 

  8. Floyd, R.W.: Algorithm 97: shortest path. Commun. ACM 5(6), 345 (1962)

    Article  Google Scholar 

  9. Klein, S., Staring, M., Murphy, K., Viergever, M., Pluim, J.: A toolbox for intensity-based medical image registration. IEEE Trans. Med. Imaging 29(1), 196–205 (2010)

    Article  Google Scholar 

  10. Lagarias, J.C., Reeds, J.A., Wright, M.H., Wright, P.E.: Convergence properties of the Nelder-Mead simplex method in low dimensions. SIAM J. Optim. 9(1), 112–147 (1998)

    Article  MathSciNet  MATH  Google Scholar 

  11. Nekolla, S., Gneiting, T., Syha, J., Deichmann, R., Haase, A.: T1 Maps by K-space reduced snapshot-FLASH MRI. J. Comput. Assist. Tomogr. 16, 327–332 (1992)

    Article  Google Scholar 

  12. Mewton, N., Liu, C.Y., Croisille, P., Bluemke, D., Lima, J.A.C.: Assessment of myocardial fibrosis with cardiovascular magnetic resonance. J. Am. Coll. Cardiol. 57(8), 891–903 (2001)

    Article  Google Scholar 

  13. Kellman, P., Hansen, M.S.: T1-mapping in the heart: accuracy and precision. J. Cardiovasc. Magn. Reson. 16, 2 (2014)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Electrical Engineering, ESAT/PSI, KU Leuven, Leuven, Belgium

    Sofie Tilborghs, Frederik Maes & Paul Suetens

  2. Department of Imaging and Pathology, Radiology, KU Leuven, Leuven, Belgium

    Tom Dresselaers & Jan Bogaert

  3. Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

    Piet Claus & Guido Claessen

  4. Medical Imaging Research Center, UZ Leuven, Herestraat 49 - 7003, 3000, Leuven, Belgium

    Sofie Tilborghs, Tom Dresselaers, Piet Claus, Jan Bogaert, Frederik Maes & Paul Suetens

Authors
  1. Sofie Tilborghs
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tom Dresselaers
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Piet Claus
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Guido Claessen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jan Bogaert
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Frederik Maes
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Paul Suetens
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sofie Tilborghs .

Editor information

Editors and Affiliations

  1. University of Toronto, Toronto, Ontario, Canada

    Mihaela Pop

  2. University of Toronto , Toronto, Ontario, Canada

    Graham A Wright

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Tilborghs, S. et al. (2017). Robust Model-Based Registration of Cardiac MR Images for T1 and ECV Mapping. In: Pop, M., Wright, G. (eds) Functional Imaging and Modelling of the Heart. FIMH 2017. Lecture Notes in Computer Science(), vol 10263. Springer, Cham. https://doi.org/10.1007/978-3-319-59448-4_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-59448-4_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59447-7

  • Online ISBN: 978-3-319-59448-4

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics

Search

Navigation