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Development of a Poroelastic Model of Spinal Cord Cavities

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Integral Methods in Science and Engineering, Volume 2

Abstract

Syringomyelia is a rare condition characterised by large fluid filled cavities in the spinal cord. Abnormal pressure changes in the cerebrospinal fluid (CSF) surrounding the cord are thought to contribute to cavity formation. A poroelastic mathematical model of the spinal cord has been built to investigate this idea. Accuracy of the model is being improved using diffusion weighted MRI (DW-MRI) to obtain updated tissue parameters.

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Author information

Authors and Affiliations

  1. School of Computing, Engineering and Mathematics, University of Brighton, Brighton, UK

    J. Venton

  2. University of Brighton, Brighton, UK

    P. J. Harris

  3. Brighton Centre for Regenerative Medicine, University of Brighton, Brighton, UK

    G. Phillips

Authors
  1. J. Venton
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  2. P. J. Harris
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  3. G. Phillips
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Corresponding author

Correspondence to J. Venton .

Editor information

Editors and Affiliations

  1. Department of Mathematics, The University of Tulsa, Tulsa, Oklahoma, USA

    Christian Constanda

  2. Department of Mathematics, The University of Tulsa, Tulsa, Oklahoma, USA

    Matteo Dalla Riva

  3. Department of Mathematics, University of Padova, Padova, Italy

    Pier Domenico Lamberti

  4. Systems Analysis, Prognosis and Control, Fraunhofer Institute for Industrial Math, Kaiserslautern, Germany

    Paolo Musolino

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Venton, J., Harris, P.J., Phillips, G. (2017). Development of a Poroelastic Model of Spinal Cord Cavities. In: Constanda, C., Dalla Riva, M., Lamberti, P., Musolino, P. (eds) Integral Methods in Science and Engineering, Volume 2. Birkhäuser, Cham. https://doi.org/10.1007/978-3-319-59387-6_27

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