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The Wireless Motility Capsule

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Gastrointestinal Motility Disorders

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Abstract

The wireless motility capsule (WMC) enables the measurement of regional and whole gut transit time in a single standardized ambulatory test. The WMC system consists of a single-use capsule, a receiver, and data processing software. The capsule is indigestible and holds sensors for pH, temperature, and pressure. Anatomic positioning is determined using measuring for pH, temperature, and pressure, enabling the definition of time of entering the stomach, time of leaving the stomach and entering the small intestine, the time of reaching the cecum, and the time of exit from the body. Data analysis and report are prepared by the display software. The sensitivity and specificity of WMC in identifying delayed gastric empting was reported to be as high as 0.87 and 0.92, respectively. Significant correlation was also reported for small bowel transit time values obtained with WMC (r = 0.69; p = 0.05) and for colon transit time y (r = 0.78 at day 2 and r = 0.59 at day 5).

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References

  1. Rao SS. Constipation: evaluation and treatment of colonic and anorectal motility disorders. Gastrointest Endosc Clin N Am. 2009;19:117–39.

    Article  PubMed  Google Scholar 

  2. Abell TL, Camilleri M, Donohoe K, et al. Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and motility society and the Society of Nuclear Medicine. J Nucl Med Technol. 2008;36:44–54.

    Article  PubMed  Google Scholar 

  3. Sarosiek I, Selover KH, Katz LA, et al. The assessment of regional gut transit times in healthy controls and patients with gastroparesis using wireless motility technology. Aliment Pharmacol Ther. 2010;31:313–22.

    CAS  PubMed  Google Scholar 

  4. Saad RJ, Hasler WL. A technical review and clinical assessment of the wireless motility capsule. Gastroenterol Hepatol (NY). 2011;7:795–804.

    Google Scholar 

  5. Rao SS, Camilleri M, Hasler WL, et al. Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and motility societies. Neurogastroenterol Motil. 2011;23:8–23.

    Article  CAS  PubMed  Google Scholar 

  6. FDA. Smartpill GI Monitoring System, version 2.0. Market approval notification 30 October 2009.

    Google Scholar 

  7. Wang YT, Mohammed SD, Farmer AD, et al. Regional gastrointestinal transit and pH studied in 215 healthy volunteers using thwireless motility capsule: influence of age, gender, study country and testing protocol. Aliment Pharmacol Ther. 2015;42:761–72.

    Article  CAS  PubMed  Google Scholar 

  8. Kuo B, McCallum RW, Koch KL, et al. Comparison of gastric emptying of a nondigestible capsule to a radiolabelled meal in healthy and gastroparetic subjects. Aliment Pharmacol Ther. 2008;27:186–96.

    Article  CAS  PubMed  Google Scholar 

  9. Green AD, Belkind-Gerson J, Surjanhata BC, et al. Wireless motility capsule test in children with upper gastrointestinal symptoms. J Pediatr. 2013;162:1181–7.

    Article  PubMed  Google Scholar 

  10. Zarate N, Mohammed SD, O’Shaughnessy E, et al. Accurate localization of a fall in pH within the ileocecal region: validation using a dual-scintigraphic technique. Am J Physiol Gastrointest Liver Physiol. 2010;299:G1276–86.

    Article  CAS  PubMed  Google Scholar 

  11. Michalek W, Semler JR, Kuo B. Impact of acid suppression on upper gastrointestinal pH and motility. Dig Dis Sci. 2011;56:1735–42.

    Article  CAS  PubMed  Google Scholar 

  12. Maqbool S, Parkman HP, Friedenberg FK. Wireless capsule motility: comparison of the Smartpill GI monitoring system with scintigraphy for measuring whole gut transit. Dig Dis Sci. 2009;54:2167–74.

    Article  PubMed  Google Scholar 

  13. Camilleri M, Thorne NK, Ringel Y, et al. Wireless pH-motility capsule for colonic transit: prospective comparison with radiopaque markers in chronic constipation. Neurogastroenterol Motil. 2010;22:874–82.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Rao SS, Kuo B, McCallum RW, et al. Investigation of colonic and whole gut transit with wireless motility capsule and Radioopaque markers in constipation. Clin Gastroenterol Hepatol. 2009;7:537–44.

    Article  PubMed  Google Scholar 

  15. Hasler WL. The use of SmartPill for gastric monitoring. Expert Rev Gastroenterol Hepatol. 2014;8:587–600.

    Article  CAS  PubMed  Google Scholar 

  16. Rao SS, Coss-Adame E, Valestin J, et al. Evaluation of constipation in older adults: radioopaque markers (ROMs) versus wireless motility capsule (WMC). Arch Gerontol Geriatr. 2012;55:289–94.

    Article  CAS  PubMed  Google Scholar 

  17. Rauch S, Krueger K, Turan A, et al. Use of wireless motility capsule to determine gastric emptying and small intestinal transit times in critically ill trauma patients. J Crit Care. 2012;27(534):e7–e12.

    Google Scholar 

  18. Gelfond D, Ma C, Semler J, et al. Intestinal pH and gastrointestinal transit profiles in cystic fibrosis patients measured by wireless motility capsule. Dig Dis Sci. 2013;58:2275–81.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Gastroenterology, Chaim Sheba Medical Center, Ramat Gan, Israel

    Dan Carter M.D., F.E.B.G.H & Eytan Bardan M.D., F.E.B.G.H

  2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

    Dan Carter M.D., F.E.B.G.H & Eytan Bardan M.D., F.E.B.G.H

Authors
  1. Dan Carter M.D., F.E.B.G.H
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  2. Eytan Bardan M.D., F.E.B.G.H
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Corresponding author

Correspondence to Dan Carter M.D., F.E.B.G.H .

Editor information

Editors and Affiliations

  1. Institute of Gastroenterology, Sheba medical Center, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel

    Eytan Bardan

  2. Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Reza Shaker

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© 2018 Springer International Publishing AG

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Carter, D., Bardan, E. (2018). The Wireless Motility Capsule. In: Bardan, E., Shaker, R. (eds) Gastrointestinal Motility Disorders . Springer, Cham. https://doi.org/10.1007/978-3-319-59352-4_34

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  • DOI: https://doi.org/10.1007/978-3-319-59352-4_34

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59350-0

  • Online ISBN: 978-3-319-59352-4

  • eBook Packages: MedicineMedicine (R0)

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