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Phytochemical Genomics of Ashwagandha

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Science of Ashwagandha: Preventive and Therapeutic Potentials

Abstract

Withania somnifera due to its characteristic secondary metabolite content is of valuable medicinal significance and thus various omics approaches have been recently gaining lots of interest. Present updates had revealed various key enzymes involved in withanolide biosynthetic pathway. Molecular markers (SSRs) resources have also been established and have provided leads to study intra and inter-specific gene diversity. Various in-vitro studies have been conducted to improve the withanolide content in this important plant. Further, emerging metabolomic area like phytochemical genomics has also been applied in case of Withania somnifera for metabolite detection and its structural validation.

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  1. CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow, 226015, UP, India

    Neelam S. Sangwan, Sandhya Tripathi, Yashdeep Srivastava & Bhawana Mishra

  2. Department of Metabolic and Structural Biology, CSIR-Central Institute of Medicinal and Aromatic Plants, PO CIMAP, Lucknow, 226015, India

    Neha Pandey

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  1. Neelam S. Sangwan
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    Sunil C. Kaul

  2. DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Biomedical Research Institute, National Institute of Advanced Industrial Science & Technology (AIST), Tsukuba, Ibaraki, Japan

    Renu Wadhwa

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Sangwan, N.S., Tripathi, S., Srivastava, Y., Mishra, B., Pandey, N. (2017). Phytochemical Genomics of Ashwagandha. In: Kaul, S., Wadhwa, R. (eds) Science of Ashwagandha: Preventive and Therapeutic Potentials. Springer, Cham. https://doi.org/10.1007/978-3-319-59192-6_1

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