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Chronic Critical Illness

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Critical Care Nutrition Therapy for Non-nutritionists

Abstract

Patients who survive an acute severe medical insult but who continue to require intensive medical care enter into a state of chronic critical illness (CCI). Nonadaptive molecular and cellular responses render CCI as a unique condition, without evolutionary precedent, that is only possible through modern medical practices [1].

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References

  1. Girard K, Raffin TA. The chronically critically ill: to save or let die? Respir Care. 1985;30(5):339–47.

    CAS  PubMed  Google Scholar 

  2. Schulman RC, Mechanick JI. Metabolic and nutrition support in the chronic critical illness syndrome. Respir Care. 2012;57(6):958–77. discussion 977–58.

    Article  PubMed  Google Scholar 

  3. Evans AS, Hosseinian L, Mohabir T, Kurtis S, Mechanick JI. Nutrition and the cardiac surgery intensive care unit patient—an update. J Cardiothorac Vasc Anesth. 2015;29(4):1044–50.

    Article  PubMed  Google Scholar 

  4. Doig GS, Simpson F, Sweetman EA, Finfer SR, Cooper DJ, Heighes PT, Davies AR, O’Leary M, Solano T, Peake S. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial. JAMA. 2013;309(20):2130–8.

    Article  CAS  PubMed  Google Scholar 

  5. Dvir D, Cohen J, Singer P. Computerized energy balance and complications in critically ill patients: an observational study. Clin Nutr. 2006;25(1):37–44.

    Article  PubMed  Google Scholar 

  6. Daly BJ, Douglas SL, Kelley CG, O’Toole E, Montenegro H. Trial of a disease management program to reduce hospital readmissions of the chronically critically ill. Chest. 2005;128(2):507–17.

    Article  PubMed  Google Scholar 

  7. Mechanick JI, Via MA, Zhao SZ, editors. Molecular nutrition. Washington, DC: Endocrine Press; 2015.

    Google Scholar 

  8. McClave SA, Taylor BE, Martindale RG, Warren MM, Johnson DR, Braunschweig C, McCarthy MS, Davanos E, Rice TW, Cresci GA, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2016;40(2):159–211.

    Article  CAS  PubMed  Google Scholar 

  9. Sanchez-Rodriguez D, Marco E, Ronquillo-Moreno N, Miralles R, Vazquez-Ibar O, Escalada F, Muniesa JM. Prevalence of malnutrition and sarcopenia in a post-acute care geriatric unit: applying the new ESPEN definition and EWGSOP criteria. Clin Nutr. 2017;36(5):1339–44.

    Google Scholar 

  10. Mogensen KM, Robinson MK, Casey JD, Gunasekera NS, Moromizato T, Rawn JD, Christopher KB. Nutritional status and mortality in the critically ill. Crit Care Med. 2015;43(12):2605–15.

    Article  CAS  PubMed  Google Scholar 

  11. Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C, et al. ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr. 2009;28(4):387–400.

    Article  PubMed  Google Scholar 

  12. McClave SA, Weijs PJ. Preservation of autophagy should not direct nutritional therapy. Curr Opin Clin Nutr Metab Care. 2015;18(2):155–61.

    Article  CAS  PubMed  Google Scholar 

  13. Heidegger CP, Berger MM, Graf S, Zingg W, Darmon P, Costanza MC, Thibault R, Pichard C. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet. 2013;381(9864):385–93.

    Article  PubMed  Google Scholar 

  14. Oshima T, Berger MM, De Waele E, Guttormsen AB, Heidegger CP, Hiesmayr M, Singer P, Wernerman J, Pichard C. Indirect calorimetry in nutritional therapy. A position paper by the ICALIC Study Group. Clin Nutr. 2017;36(3):651–62.

    Article  PubMed  Google Scholar 

  15. Kruizenga HM, Hofsteenge GH, Weijs PJ. Predicting resting energy expenditure in underweight, normal weight, overweight, and obese adult hospital patients. Nutr Metab (Lond). 2016;13:85.

    Article  Google Scholar 

  16. Dyson JK, Thompson N. Adult parenteral nutrition in the North of England: a region-wide audit. BMJ Open. 2017;7(1):e012663.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med. 2011;365(6):506–17.

    Article  CAS  PubMed  Google Scholar 

  18. Koekkoek WA, van Zanten AR. Antioxidant vitamins and trace elements in critical illness. Nutr Clin Pract. 2016;31(4):457–74.

    Article  CAS  PubMed  Google Scholar 

  19. Berger MM, Soguel L, Shenkin A, Revelly JP, Pinget C, Baines M, Chiolero RL. Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients. Crit Care. 2008;12(4):R101.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Bonafe L, Berger MM, Que YA, Mechanick JI. Carnitine deficiency in chronic critical illness. Curr Opin Clin Nutr Metab Care. 2014;17(2):200–9.

    Article  CAS  PubMed  Google Scholar 

  21. Via MA, Gallagher EJ, Mechanick JI. Bone physiology and therapeutics in chronic critical illness. Ann N Y Acad Sci. 2010;1211:85–94.

    Article  CAS  PubMed  Google Scholar 

  22. Van den Berghe G, Van Roosbroeck D, Vanhove P, Wouters PJ, De Pourcq L, Bouillon R. Bone turnover in prolonged critical illness: effect of vitamin D. J Clin Endocrinol Metab. 2003;88(10):4623–32.

    Article  PubMed  Google Scholar 

  23. Amrein K, Sourij H, Wagner G, Holl A, Pieber TR, Smolle KH, Stojakovic T, Schnedl C, Dobnig H. Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study. Crit Care. 2011;15(2):R104.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Ben-Hamouda N, Charriere M, Voirol P, Berger MM. Massive copper and selenium losses cause life-threatening deficiencies during prolonged continuous renal replacement. Nutrition. 2017;34:71–5.

    Article  CAS  PubMed  Google Scholar 

  25. Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Meduri GU. Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review. JAMA. 2009;301(22):2362–75.

    Article  CAS  PubMed  Google Scholar 

  26. Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF, Vundelinckx G, Hinds CJ. Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med. 1999;341(11):785–92.

    Article  CAS  PubMed  Google Scholar 

  27. Garber JR, Cobin RH, Gharib H, Hennessey JV, Klein I, Mechanick JI, Pessah-Pollack R, Singer PA, Woeber KA. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract. 2012;18(6):988–1028.

    Article  PubMed  Google Scholar 

  28. Nierman DM, Mechanick JI. Hypotestosteronemia in chronically critically ill men. Crit Care Med. 1999;27(11):2418–21.

    Article  CAS  PubMed  Google Scholar 

  29. Schulman RC, Moshier EL, Rho L, Casey MF, Godbold JH, Zaidi M, Mechanick JI. Intravenous pamidronate is associated with reduced mortality in patients with chronic critical illness. Endocr Pract. 2016;22(7):799–808.

    Article  PubMed  Google Scholar 

  30. Via MA, Potenza MV, Hollander J, Liu X, Peng Y, Li J, Sun L, Zaidi M, Mechanick JI. Intravenous ibandronate acutely reduces bone hyperresorption in chronic critical illness. J Intensive Care Med. 2012;27(5):312–8.

    Article  PubMed  Google Scholar 

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Correspondence to Michael A. Via .

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Via, M.A., Mechanick, J.I. (2018). Chronic Critical Illness. In: Berger, M. (eds) Critical Care Nutrition Therapy for Non-nutritionists. Springer, Cham. https://doi.org/10.1007/978-3-319-58652-6_12

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  • DOI: https://doi.org/10.1007/978-3-319-58652-6_12

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  • Publisher Name: Springer, Cham

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