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Metal Allergy pp 495–506Cite as

Metal Allergy in Children

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Abstract

Metals are significant provocateurs of allergic contact dermatitis in children. Skin barrier defects due to filaggrin gene mutations confer an increased risk of expression of atopic dermatitis, a potential for increased absorption of metals across a defective barrier, and a risk for contact sensitization to metals, particularly nickel. This chapter discusses the complex interplay of environmental and intrinsic factors with respect to metal contact sensitization in children.

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Author information

Authors and Affiliations

  1. School of Medicine, Loma Linda University, Loma Linda, CA, 92350, USA

    Chandler Rundle

  2. Department of Dermatology, Eastern Virginia Medical School, Norfolk, VA, 23507, USA

    Nikoleta Brankov

  3. Department of Dermatology, Loma Linda University, Loma Linda, CA, 92354, USA

    Sharon E. Jacob

Authors
  1. Chandler Rundle
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  2. Nikoleta Brankov
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  3. Sharon E. Jacob
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Corresponding author

Correspondence to Sharon E. Jacob .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, USA

    Jennifer K Chen

  2. Department of Dermatology and Allergy Herlev and Gentofte Hospital University of Copenhagen, Hellerup, Denmark

    Jacob P. Thyssen

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Rundle, C., Brankov, N., Jacob, S.E. (2018). Metal Allergy in Children. In: Chen, J., Thyssen, J. (eds) Metal Allergy. Springer, Cham. https://doi.org/10.1007/978-3-319-58503-1_37

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  • DOI: https://doi.org/10.1007/978-3-319-58503-1_37

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