Screening for Fetal Aneuploidy

  • Kate C. Arnold
  • Caroline J. Flint


The goal of screening is to identify fetuses at increased risk of having a genetic disorder. Screening for aneuploidy can be accomplished using different modalities at specific gestational ages. Examples include first trimester screen, second trimester screen, integrated screen, and sequential screen. Screening should be offered to all women as part of comprehensive prenatal care [1].


Trisomy Prenatal screening Quad screen Serum screen Aneuploidy Genetic disorder 


  1. 1.
    Gabbe SG, Niebyl JR, Simpson JL, Landon MB, Galan HL, Jauniaux ERM, Driscoll DA. Obstetrics: normal and problem pregnancies. Chapter 10. 6th ed. Philadelphia, PA: Elsevier; 2012.Google Scholar
  2. 2.
    American College of Obstetricians and Gynecologists. Practice bulletin no. 163: screening for fetal aneuploidy. Obstet Gynecol. 2016;127(5):e123–37.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Kate C. Arnold
    • 1
  • Caroline J. Flint
    • 1
  1. 1.Department of OB/GYNUniversity of Oklahoma HSCOklahoma CityUSA

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