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Thyroid Disease in Pregnancy

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Abstract

Pregnancy results in increased thyroxine-binding globulin and increased thyroid-stimulating hormone receptor activation due to human chorionic gonadotropin. This results in increased secretion of thyroid hormones. In hyperthyroidism patients, propylthiouracil and methimazole are the drugs of choice depending on fetal gestational age. More than half of patients with hypothyroidism will need to increase the dose of their replacement during pregnancy. Thyroid storm is rare but life-threatening and should be managed in an intensive care unit [1].

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  1. Gabbe SG, Niebyl JR, Simpson JL, Landon MB, Galan HL, Jauniaux ERM, Driscoll DA. Obstetrics: normal and problem pregnancies. Chapter 40. 6th ed. Philadelphia, PA: Elsevier; 2012.

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  2. American College of Obstetricians and Gynecologists. Practice bulletin no. 148: thyroid disease in pregnancy. Obstet Gynecol. 2015;125:996–1005.

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Arnold, K.C., Flint, C.J. (2017). Thyroid Disease in Pregnancy. In: Obstetrics Essentials. Springer, Cham. https://doi.org/10.1007/978-3-319-57675-6_30

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  • DOI: https://doi.org/10.1007/978-3-319-57675-6_30

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-57674-9

  • Online ISBN: 978-3-319-57675-6

  • eBook Packages: MedicineMedicine (R0)

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