Abstract
Tuberculosis (TB) is one of the leading causes of mortality and morbidity worldwide especially in the developing world. However, its incidence is on a rise even in the Western world partly due to immigration from the developing countries and partly due to the opportunistic infections in patients with acquired immunodeficiency syndrome (AIDS) [1, 2]. WHO gives an estimate that one third of the world’s population is infected with the tubercle bacilli. Further, new resistant strains have emerged which are difficult to treat and cause deep-seated infection [2]. Thus, the control of chronic and insidious infectious diseases such as Tb may become a daunting task, and it may continue to remain as one of the leading causes of morbidity and mortality with newer manifestations and previously unseen presentations.
Tuberculosis (Tb) is one of the leading causes of mortality and morbidity worldwide especially in the developing world. However, its incidence is on a rise even in the Western world partly due to immigration from the developing countries and partly due to the opportunistic infections in patients with acquired immunodeficiency syndrome (AIDS) [1, 2]. WHO gives an estimate that one third of the world’s population is infected with the tubercle bacilli. Further, new resistant strains have emerged which are difficult to treat and cause deep-seated infection [2]. Thus, the control of chronic and insidious infectious diseases such as Tb may become a daunting task, and it may continue to remain as one of the leading causes of morbidity and mortality with newer manifestations and previously unseen presentations.
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References
Barnes PF, Bloch AB, Davidson PT, Snider Jr DE. Tuberculosis in patients with human immunodeficiency virus infection [review]. N Engl J Med. 1991;324:1644–50.
Brudney K, Dobkin J. Resurgent tuberculosis in New York City. Human immunodeficiency virus, homelessness, and the decline of tuberculosis control programs. Am Rev Respir Dis. 1991;144:745–9.
Tabbara KF. Tuberculosis. Curr Opin Ophthalmol. 2007;18:493–501.
Islam SM, Tabbara KF. Causes of uveitis at the eye Center in Saudi Arabia: a retrospective review. Ophthalmic Epidemiol. 2002;9:239–49.
Chaurasia S, Ramappa M, Murthy SI, Vemuganti GK, Fernandes M, Sharma S, Sangwan V. Chronic conjunctivitis due to Mycobacterium tuberculosis. Int Ophthalmol. 2014;34(3):655–60.
Jackson WB. Differentiating conjunctivitis of diverse origins. Surv Ophthalmol. 1993;38(Suppl):91–104.
Rohatgi J, Dhaliwal U. Phlyctenular eye disease: a reappraisal. Jpn J Ophthalmol. 2000;44(22):146–50.
Lahiri K, Landge A, Gahlowt P, Bhattar A, Rai R. Phlyctenular conjunctivitis and tuberculosis. Pediatr Infect Dis J. 2015;34(6):675.
Beauchamp GR, Gillete TE, Friendly DS. Phlyctenular keratoconjunctivitis. J Pediatr Ophthalmol Strabismus. 1981;18(3):22–8.
Tabbara KF. Phlyctenulosis. In: Roy FH, Fraunfelder FT, Fraunfelder FW, editors. Current ocular therapy. 6th ed. London: Elsevier.
Lanier JD. Phlyctenular keratoconjunctivitis with special reference to the staphylococcal type. Transactions of the Pacific Coast Oto-Ophthalmologic Society Annual Meeting. 1974;55:237–52.
Ostler HB. Corneal perforation in nontuberculous(staphylococcal) phlyctenular keratoconjunctivitis. Am J Ophthalmol. 1975;79:446–8.
Abu El Asrar AM, Geboes K, Maudgal PC, Emarah MH, Missotten L, Desmet V. Immunocytological study of phlyctenular eye disease. Int Ophthalmol. 1987;10(1):33–9.
Doan S, Gabison E, Gatinel D, Duong MH, Abitbol O, Hoang-Xuan T. Topical cyclosporine a in severe steroid-dependent childhood phlyctenular keratoconjunctivitis. Am J Ophthalmol. 2006;141(1):62–6.
Bansal R, Gupta A, Gupta V, et al. Role of anti-tubercular therapy in uveitis with latent/manifest tuberculosis. Am J Ophthalmol. 2008;146:772–9.
Eyre JWH. Tuberculosis of the conjunctiva: its etiology, pathology, and diagnosis. Lancet. 1912;1:1319–28.
Biswas J, Kumar SK, Rupauliha P, et al. Detection of Mycobacterium tuberculosis by nested polymerase chain reaction in a case of subconjunctival tuberculosis. Cornea. 2002;21:123–5.
Woods AC. Ocular tuberculosis. In: Sorsby A, editor. Modern ophthalmology. Philadelphia: JB Lippincott; 1972. p. 105–40.
Kamal S, Kumar R, Kumar S, Goel R. Bilateral interstitial keratitis and granulomatous uveitis of tubercular origin. Eye Contact Lens. 2014;40:e13–5.
Arora R, Mehta S, Gupta D, Goyal J. Bilateral disciform keratitis as the presenting feature of extrapulmonary tuberculosis. Br J Ophthalmol. 2010;94:809–10.
Bayraktutar BN, Uçakhan-Gündüz Ö. Ocular tuberculosis with ProgressiveUnilateral corneal melting. Case Rep Ophthalmol. 2015;6(3):293–7.
Arora T, Sharma N, Shashni A, Titiyal JS. Peripheral ulcerative keratitis associated with chronic malabsorption syndrome and miliary tuberculosis in a child. Oman J Ophthalmol. 2015;8(3):205–7.
Nanda M, Pflugfelder SC, Holland S. Mycobacterium tuberculosis scleritis. Am J Ophthalmol. 1989;108:736–7.
Gupta A, Gupta V, Pandav SS, Gupta A. Posterior scleritis associated with systemic tuberculosis. Indian J Ophthalmol. 2003;51:347–9.
Lee JY. Diagnosis and treatment of Extrapulmonary tuberculosis. Tuberc Respir Dis. 2015;78(2):47–55.
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Namrata Sharma and Neelima Aron declare that they have no conflict of interest. No human or animal studies were carried out by the authors for this chapter.
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Sharma, N., Aron, N. (2017). Conjunctival and Corneal Tuberculosis. In: Kumar, A., Chawla, R., Sharma, N. (eds) Ocular Tuberculosis. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-57520-9_12
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DOI: https://doi.org/10.1007/978-3-319-57520-9_12
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