Abstract
This chapter reviews the discovery of nude mice, their characterization as athymic and how Dr. Jorgen Rygaard and his colleagues used nude mice to establish the first in vivo human cancer patient model. This chapter also reviews how the nude mouse was disseminated to major cancer centers throughout the world and became the standard model of growing human patient tumors in the laboratory.
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Hoffman, R.M. (2017). In Memoriam: Jørgen Rygaard (1934–2016), Father of Patient-Derived Mouse Models of Cancer and Modern Cancer Research. In: Hoffman, R. (eds) Patient-Derived Mouse Models of Cancer . Molecular and Translational Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-57424-0_1
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DOI: https://doi.org/10.1007/978-3-319-57424-0_1
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