Abstract
This chapter outlines the methods and applications of X-ray computed tomography (CT) imaging to analyze soft tissue and skeletal muscle density and volume in the context of modern challenges in the field of translational myology. The approaches described here use medical imaging processing techniques and computational methods to quantify muscle morphology, illustrate changes with 3D models, develop numerical profiles specific for each individual, and assess muscle changes due to targeted medical treatment.
Applications of these methodologies are summarized in this chapter: (1) subject-specific muscle profiling and association with age, (2) 3D modeling to illustrate and quantify muscle degeneration and its partial reversal via functional electrical stimulation (FES), and (3) muscle profiling to highlight recovery following total hip arthroplasty (THA).
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References
Edmunds KJ, Gargiulo P (2015) Imaging approaches in functional assessment of implantable myogenic biomaterials and engineered muscle tissue. Eur J Transl Myol 25(2):4847. doi:10.4081/ejtm.2015.4847
Metter EJ, Talbot LA, Schrager M, Conwit R (2002) Skeletal muscle strength as a predictor of all-cause mortality in healthy men. J Gerontol A Biol Sci Med Sci 57(10):B359–B365
Rantanen T (2000) Muscle strength and body mass index as long-term predictors of mortality in initialle healthy men. J Gerontol 55A(3):168–173
Newman AB, Kupelian V, Visser M, Simonsick EM, Goodpaster BH, Kritchevsky SB, Harris TB (2006) Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci 61(1):72–77
Goodpaster BH, Carlson CL, Visser M, Kelley DE, Scherzinger A, Harris TB, Stamm E, Newman AB (2001) Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study. J Appl Physiol 90:2157–2165
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD (1998) Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 147(8):755–763
Janssen I, Heymsfield SB, Ross R (2002) Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 50(5):889–896
Newman AB, Kupelian V, Visser M, Simonsick E, Goodpaster B, Nevitt M, Kritchevsky SB, Tylavsky FA, Rubin SM, Harris TB (2003) Sarcopenia: alternative definitions and associations with lower extremity function. J Am Geriatr Soc 51:1602–1609. doi:10.1046/j.1532-5415.2003.51534.x
Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R (2004) The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc. doi:10.1111/j.1532-5415.2004.52014.x
Helgason T, Gargiulo P, Jóhannesdóttir F, Ingvarsson P, Knútsdóttir S, Gudmundsdóttir V, Yngvason S (2005) Monitoring muscle growth and tissue changes induced by electrical stimulation of denervated degenerated muscles with CT and stereolithographic 3D modeling. Artif Organs 29:440–443. doi:10.1111/j.1525-1594.2005.29073.x
Carraro U, Edmunds KJ, Gargiulo P (2015) 3D false color computed tomography for diagnosis and follow-up of permanently denervated human femoral muscles submitted to functional electrical stimulation. Eur J Transl Myol 25(2):129–140
Edmunds KJ, Gíslason MK, Arnadottir ID, Marcante A, Piccione F, Gargiulo P (2016) Quantitative computed tomography and image analysis for advanced muscle assessment. Eur J Transl Myol 26(2):6015. doi:10.4081/ejtm.2016.6015
Magnússon B, Pétursson Þ, Edmunds K et al (2015) Improving planning and post-operative assessment for total hip arthroplasty. Eur J Transl Myol 25(2):4913. doi:10.4081/ejtm.2015.4913
Pétursson Þ, Edmunds KJ, Gíslason MK et al (2015) Bone mineral density and fracture risk assessment to optimize prosthesis selection in total hip replacement. Comput Math Methods Med 2015:162481. doi:10.1155/2015/162481
Gargiulo P, Péturssone T et al (2003) Assessment of total hip arthroplasty by means of computed tomography 3D models and fracture risk evaluation. Artif Organs 37(6):567–573
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Gargiulo, P., Edmunds, K.J., Arnadottir, I.D., Carraro, U., Gíslason, M.K. (2018). Muscle Assessment Using 3D Modeling and Soft Tissue CT Profiling. In: Masiero, S., Carraro, U. (eds) Rehabilitation Medicine for Elderly Patients. Practical Issues in Geriatrics. Springer, Cham. https://doi.org/10.1007/978-3-319-57406-6_24
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DOI: https://doi.org/10.1007/978-3-319-57406-6_24
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