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Association of Nutrients with Biomarkers of Alzheimer’s Disease

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GeNeDis 2016

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 987))

Abstract

Prospective cohort studies, cross-sectional surveys, autopsy studies and intervention clinical trials that investigated the association between nutrients and Alzheimer’s disease (AD) have been reviewed. To estimate the relationship between specific nutrient intake and the risk of AD, Cochrane Library, PubMed, EMBASE, and the Fisher Center for Alzheimer’s Research Foundation were searched for this purpose. Most published observational studies found an inverse relationship between vitamins, n-3 fatty acids and AD. The majority of intervention studies support the beneficial effect of combined vitamins and n-3 fatty acids providing them in the early stages of the disease. Only vitamin E and Zn supplementation failed to show any significant difference on the study population. On the other hand, high dietary intake of saturated fat and brain metal accumulation were positively associated with the incidence of AD.

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Authors and Affiliations

  1. Department of Informatics, Ionian University, Bioinformatics and Human Electrophysiology Lab (BiHeLab), Corfu, Greece

    Efstathia G. Kalli

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  1. Efstathia G. Kalli
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Correspondence to Efstathia G. Kalli .

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  1. Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Ionian University, Corfu, Greece

    Panayiotis Vlamos

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Kalli, E.G. (2017). Association of Nutrients with Biomarkers of Alzheimer’s Disease. In: Vlamos, P. (eds) GeNeDis 2016. Advances in Experimental Medicine and Biology, vol 987. Springer, Cham. https://doi.org/10.1007/978-3-319-57379-3_23

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