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Fatigue in Arthritis: A Multidimensional Phenomenon with Impact on Quality of Life

Fatigue and Quality of Life in Arthritis

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Abstract

An important factor which influences the quality of life of patients with arthritis is the fatigue they experience. The purpose of this study was to assess the relationship between fatigue and quality of life among patients with osteoarthritis and rheumatoid arthritis. Between January 2015 and March 2015, 179 patients with osteoarthritis and rheumatoid arthritis completed the Fatigue Assessment Scale and the Missoula-VITAS Quality of Life Index-15 (MVQoLI-15). The study was conducted in Rehabilitation Centers located in the area of Peloponnese, Greece. Data related to sociodemographic characteristics and their individual medical histories were recorded. Statistical analysis was performed using the IBM SPSS Statistics version 19. The analysis did not reveal statistically significant correlation between fatigue and quality of life neither in the total sample nor among patients with osteoarthritis (r = −0.159; p = 0.126) or rheumatoid arthritis. However, there was a statistically significant relationship between some aspects of fatigue and dimensions of quality of life. Osteoarthritis patients had statistically significant lower MVQoLI-15 score than rheumatoid arthritis patients (13.73 ± 1.811 vs 14.61 ± 1.734) and lower FAS score than rheumatoid patients (26.14 ± 3.668 vs 29.94 ± 3.377) (p-value < 0.001). The finding that different aspects of fatigue may affect dimensions of quality of life may help health care professionals by proposing the early treatment of fatigue in order to gain benefits for quality of life.

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References

  1. Jorgensen, R. 2008. Chronic Fatigue: An Evolutionary Concept Analysis. Journal of Advanced Nursing 63: 199–207.

    Article  PubMed  Google Scholar 

  2. Zyga, S., V. Alikari, A. Sachlas, et al. 2015. Assessment of Fatigue in End Stage Renal Disease Patients Undergoing Hemodialysis: Prevalence and Associated Factors. Medieval Archaeology 69: 376–380.

    Google Scholar 

  3. Frank, M. 2014. Cancer Related Fatigue Syndrome in Neoplastic Diseases. Przegląd Menopauzalny 13: 352–355.

    Google Scholar 

  4. Tabrizi, F.M., and M. Radfar. 2015. Fatigue, Sleep Quality, and Disability in Relation to Quality of Life in Multiple Sclerosis. International Journal of MS Care 17: 268–274.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Yuen, H.K., and M.A. Cunningham. 2014. Optimal Management of Fatigue in Patients with Systemic Lupus Erythematosus: A Systematic Review. Therapeutics and Clinical Risk Management 10: 775–786.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Gong, G., and J. Mao. 2016. Health-Related Quality of Life Among Chinese Patients with Rheumatoid Arthritis: The Predictive Roles of Fatigue, Functional Disability, Self-Efficacy, and Social Support. Nursing Research 65: 55–67.

    Article  PubMed  Google Scholar 

  7. Gignac, M.A., A.M. Davis, G. Hawker, et al. 2006. “What Do You Expect? You’re Just Getting Older”: A Comparison of Perceived Osteoarthritis-Related and Aging-Related Health Experiences in Middle- and Older-Age Adults. Arthritis and Rheumatism 55: 905–912.

    Article  PubMed  Google Scholar 

  8. Power, J.D., E.M. Badley, M.R. French, et al. 2008. Fatigue in Osteoarthritis: A Qualitative Study. BMC Musculoskeletal Disorders 9: 63.

    Article  PubMed  PubMed Central  Google Scholar 

  9. DeJean, D., M. Giacomini, M. Vanstone, et al. 2013. Patient Experiences of Depression and Anxiety with Chronic Disease: A Systematic Review and Qualitative Meta-Synthesis. Ontario Health Technology Assessment Series 13: 1–33.

    CAS  Google Scholar 

  10. McBeth, J., B. Tomenson, C.A. Chew-Graham, et al. 2015. Common and Unique Associated Factors for Medically Unexplained Chronic Widespread Pain and Chronic Fatigue. Journal of Psychosomatic Research 79: 484–491.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Nikolaus, S., C. Bode, E. Taal, et al. 2013. Fatigue and Factors Related to Fatigue in Rheumatoid Arthritis: A Systematic Review. Arthritis Care and Research 65: 1128–1146.

    Article  PubMed  Google Scholar 

  12. Stebbings, S., P. Herbison, T.C. Doyle, et al. 2013. A Comparison of Fatigue Correlates in Rheumatoid Arthritis and Osteoarthritis: Disparity in Associations with Disability, Anxiety and Sleep Disturbance. Rheumatology (Oxford) 49: 361–367.

    Article  Google Scholar 

  13. Stone, A.A., J.E. Broderick, L.S. Porter, et al. 1997. The Experience of Rheumatoid Arthritis Pain and Fatigue: Examining Momentary Reports and Correlates Over One Week. Arthritis Care & Research 10: 185–193.

    Article  CAS  Google Scholar 

  14. Rupp, I., H.C. Boshuizen, C.E. Jacobi, et al. 2004. Arthritis and Rheumatism 51: 578–585.

    Article  PubMed  Google Scholar 

  15. Ahlmén, M., U. Nordenskiöld, B. Archenholtz, et al. 2005. Rheumatology Outcomes: The Patient’s Perspective. A Multicentre Focus Group Interview Study of Swedish Rheumatoid Arthritis Patients. Rheumatology (Oxford) 44: 105–110.

    Article  Google Scholar 

  16. Hewlett, S., Z. Cockshott, M. Byron, et al. 2005. Patients’ Perceptions of Fatigue in Rheumatoid Arthritis: Overwhelming, Uncontrollable, Ignored. Arthritis and Rheumatism 53: 697–702.

    Article  PubMed  Google Scholar 

  17. Repping-Wuts, H., R. Uitterhoeve, P. van Riel, et al. 2008. Fatigue as Experienced by Patients with Rheumatoid Arthritis (RA): A Qualitative Study. International Journal of Nursing Studies 45: 995–1002.

    Article  PubMed  Google Scholar 

  18. Doeglas, D. 2000. Functional Ability, Social Support and Quality of Life: A Longitudinal Study in Patients with Early Rheumatoid Arthritis [Dissertation]. Groningen: University of Groningen.

    Google Scholar 

  19. Theofilou, P., A. Aroni, M. Ralli, et al. 2013. Measuring Health Related Quality of Life in Hemodialysis Patients. Psychometric Properties of the Missoula-VITAS Quality of Life Index (MVQOLI-15) in Greece. Health Psychology Research 1: e17.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Alikari, V., E. Fradelos, A. Sachlas, et al. 2016. Reliability and Validity of the Greek Version of “The Fatigue Assessment Scale”. Archives of Hellenic Medicine 33: 231–238.

    Google Scholar 

  21. Michielsen, H.J., J. De Vries, and G.L. Van Heck. 2003. Psychometric Qualities of a Brief Self-Rated Fatigue Measure: The Fatigue Assessment Scale. Journal of Psychosomatic Research 54: 345–352.

    Article  PubMed  Google Scholar 

  22. De Vries, J., H. Michielsen, G.L. Van Heck, et al. 2004. Measuring Fatigue in Sarcoidosis: The Fatigue Assessment Scale (FAS). British Journal of Health Psychology 9: 279–291.

    Article  PubMed  Google Scholar 

  23. Michielsen, H.J., J. De Vries, M. Drent, et al. 2005. Psychometric Qualities of the Fatigue Assessment Scale in Croatian Sarcoidosis Patients. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases 22: 133–138.

    PubMed  Google Scholar 

  24. Smith, O.R., H.J. Michielsen, and A.J. Pelle. 2007. Symptoms of Fatigue in Chronic Heart Failure Patients: Clinical and Psychological Predictors. European Journal of Heart Failure 9: 922–927.

    Article  PubMed  Google Scholar 

  25. Mancuso, C.A., M. Rincon, W. Sayles, et al. 2006. Psychosocial Variables and Fatigue: A Longitudinal Study Comparing Individuals with Rheumatoid Arthritis and Healthy Controls. The Journal of Rheumatology 33: 1496–1502.

    PubMed  Google Scholar 

  26. Wolfe, F., and K. Michaud. 2004. Fatigue, Rheumatoid Arthritis, and Anti-Tumor Necrosis Factor Therapy: An Investigation in 24,831 Patients. The Journal of Rheumatology 31: 2115–2120.

    CAS  PubMed  Google Scholar 

  27. Pollard, L.C., E.H. Choy, J. Gonzalez, et al. 2006. Fatigue in Rheumatoid Arthritis Reflects Pain, Not Disease Activity. Rheumatology (Oxford) 45: 885–889.

    Article  CAS  Google Scholar 

  28. Wolfe, F. 2004. Fatigue Assessments in Rheumatoid Arthritis: Comparative Performance of Visual Analog Scales and Longer Fatigue Questionnaires in 7760 Patients. The Journal of Rheumatology 31: 1896–1902.

    PubMed  Google Scholar 

  29. van Tubergen, A., J. Coenen, R. Landewé, et al. 2002. Assessment of Fatigue in Patients with Ankylosing Spondylitis: A Psychometric Analysis. Arthritis and Rheumatism 47: 8–16.

    Article  PubMed  Google Scholar 

  30. Baetz, M., and R. Bowen. 2008. Chronic Pain and Fatigue: Associations with Religion and Spirituality. Pain Research & Management 13: 383–388.

    Article  CAS  Google Scholar 

  31. Wolfe, F., K. Michaud, T. Li, et al. 2006. Sleep Disturbance in Patients with Rheumatoid Arthritis: Evaluation by Medical Outcomes Study and Visual Analog Sleep Scales. The Journal of Rheumatology 33: 1942–1951.

    PubMed  Google Scholar 

  32. Repping-Wuts, H., P. van Riel, and T. van Achterberg. 2009. Fatigue in Patients with Rheumatoid Arthritis: What is Known and What is Needed. Rheumatology (Oxford) 48: 207–209.

    Article  CAS  Google Scholar 

  33. Butbul Aviel, Y., R. Stremler, S.M. Benseler, et al. 2011. Sleep and Fatigue and the Relationship to Pain, Disease Activity and Quality of Life in Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis. Rheumatology (Oxford) 50: 2051–2060.

    Article  Google Scholar 

  34. Turan, Y., Z. Kocaağa, H. Koçyiğit, et al. 2010. Correlation of Fatigue with Clinical Parameters and Quality of Life in Rheumatoid Arthritis. Turkish Journal of Rheumatology 25: 63–67.

    Article  Google Scholar 

  35. Zyga, S. 2012. Maintaining the Identity and Self-Worth in Patients with Severe Illness or Injury. International Journal of Caring Sciences 5 (1): 1–2.

    Google Scholar 

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Acknowledgements

The authors thank patients, staff and the Administration of the Rehabilitation Centers in Peloponnese region.

Conflicts of Interest and Source of Funding

The authors declare no conflict of interest. This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Correspondence to Sofia Zyga .

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Alikari, V. et al. (2017). Fatigue in Arthritis: A Multidimensional Phenomenon with Impact on Quality of Life. In: Vlamos, P. (eds) GeNeDis 2016. Advances in Experimental Medicine and Biology, vol 987. Springer, Cham. https://doi.org/10.1007/978-3-319-57379-3_22

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