Cell Therapy pp 297-317 | Cite as

Stem Cell Therapy in Duchenne Muscular Dystrophy

  • Mirella Meregalli
  • Marzia Belicchi
  • Yvan TorrenteEmail author
Part of the Molecular and Translational Medicine book series (MOLEMED)


Here, we will describe the therapeutic potential of stem cell in the treatment of Duchenne muscular dystrophy (DMD). Moreover, we will examine pros and cons in the use of stem cells in clinical trials and the set of problems linked to the fine-tuning of protocols finalized to the generation of large numbers of transplantable cells. We will describe the experimental studies focused on the analysis of survival and functional efficacy of the grafted cells and the possible onset of adverse effects, such as immune rejection and tumor formation.


Duchenne muscular dystrophy DMD Stem cells Cell therapy Clinical trials 



This work was supported by Associazione Gli Amici di Emanuele—Fondo DMD Onlus, Associazione Amici del Centro Dino Ferrari, s.r.l.

Conflict of Interest Statement

The authors declare that no commercial or financial conflict of interests no longer exist.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Mirella Meregalli
    • 1
  • Marzia Belicchi
    • 1
  • Yvan Torrente
    • 1
    Email author
  1. 1.Department of Pathophysiology and TransplantationFondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Centro Dino FerrariMilanItaly

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