This book considers four different imaging modalities THz-TPI, MRI, fundus imaging and OCT. It is shown that, because of the complementarity between THz-TPI and MRI datasets along with OCT techniques, there is potential for developing a unified biomedical signal processing framework. THz-TPI is currently being explored as a viable alternative imaging modality to assess disease progression in a non-invasive manner. DCE-MRI is well established and is regularly used in clinical environments. In contrast, TPI has yet to gain popularity although there is a general recognition of its potential to provide complementary information to clinicians.