Central Pruritus

  • Sergio Canavero
  • Vincenzo Bonicalzi


Central pruritus (CP) following CNS damage (Tables 5.1 and 5.2) has not received adequate recognition as part of the spectrum of CP (while it is well known as a consequence of PNP). Pruritus can blend with pain or dysesthesias or present singly (note that pain-insensitive patients are also itch-insensitive: [38]). Most likely, patients may complain of itching, but the treating physician may dismiss it until scratching makes the problem visible. Pruritus tends to be continuous, but may also present in paroxysms or bouts. Both brain and cord lesions have been described. In the brain, stroke is the main trigger, while in the cord, intramedullary masses are mainly responsible. Central pruritus is also commonly observed in multiple sclerosis, but also in neuromyelitis optica [39–41].


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Sergio Canavero
    • 1
  • Vincenzo Bonicalzi
    • 2
  1. 1.HEAVEN/GEMINI International Collaborative GroupTurinItaly
  2. 2.AOUCittà della Salute e della Scienza di Torino, Department of Neurosciences, Rita Levi MontalciniUniversità di TorinoTurinItaly

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