Abstract
In the present work, some new 5-[2(3)-dialkylamino alkoxy] Indole 2,3-diones were prepared from 5-hydroxy isatin. A mixture of 5-hydroxy isatin, dialkylamino alkylhalide in alcoholic potassium hydroxide was stirred at room temperature for 6 h to get the 5-[2(3)-dialkylamino alkoxy] Indole 2,3-diones. The structures of the products were characterized by IR, NMR, MASS Spectral studies. All the compounds were evaluated for anti-inflammatory activity. Some of these compounds showed good anti-inflammatory activity compared with standard compound Indomethacin.
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Acknowledgments
The First author would like to thank the UGC, New Delhi for providing financial support. Authors are thankful to Principal University College of Pharmaceutical Sciences, Kakatiya University, Warangal for providing facilities.
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Swathi, K., Manasa, C., Sarangapani, M. (2017). Development of Novel Indole Molecules for the Screening of Anti-Inflammatory Activity. In: Vlamos, P. (eds) GeNeDis 2016. Advances in Experimental Medicine and Biology, vol 988. Springer, Cham. https://doi.org/10.1007/978-3-319-56246-9_11
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DOI: https://doi.org/10.1007/978-3-319-56246-9_11
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