Abstract
Laryngeal edema occurs when the larynx is included in the treatment field and may impact the voice. Laryngeal edema accompanied by hoarseness is a common acute side effect in radiation therapy of laryngeal and hypopharyngeal carcinoma and whenever the neck is irradiated [1]; however, no studies have reported its incidence as an acute side effect. It has been estimated that 15–59% of patients with head and neck cancers develop grade 2 or higher laryngeal edema within 2 years after radiation therapy [2].
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References
Mardini G, Salgado C, Chen H (2010) Esophagus and hypopharyngeal reconstruction. Semin Plast Surg 24(2):127–136
Bae JS, Roh JL, Lee SW, Kim SB, Kim JS, Lee JH, Choi SH, Nam SY, Kim SY (2012) Laryngeal edema after radiotherapy in patients with squamous cell carcinomas of the larynx and hypopharynx. Oral Oncol 48(9):853–858
Barnett G, West C, Dunning A, Elliott R, Coles C, Pharoah P, Burnet N (2009) Normal tissue reactions to radiotherapy towards tailoring treatment dose by genotype. Nat Rev Cancer 9(2):134–142
Di Maggio F, Minafra L, Forte GI, Cammarata F, Lio D, Messa C, Gilardi M, Bravatà V (2015) Portrait of inflammatory response to ionizing radiation treatment. J Inflamm (Lond) 12:14
Lazarus C (2009) Effects of chemoradiotherapy on voice and swallowing. Surgery 17(3):172–178
Sato K, Nakashima T (2008) Effect of irradiation on the human laryngeal glands. Ann Otol Rhinol Laryngol 117(10):734–739
Fu KK, Woodhouse RJ, Quivey JM, Phillips TL, Dedo HH (1982) The significance of laryngeal edema following radiotherapy of carcinoma of the vocal cord. Cancer 49(4):655–658
Sanguineti G, Adapala P, Endres EJ et al (2007) Dosimetric predictors of laryngeal edema. Int J Radiat Oncol Biol Phys 68(3):741–749
KK F, Woofhouse RJ, Quivey JM et al (1982) The significance of laryngeal edema following radiotherapy of carcinoma of the vocal cord. Cancer 49:6555–6558
Mendenhall WM, Parsons JT, Stringer SP, Cassisi NJ, Million RR (1990) The role of radiation therapy in laryngeal cancer. CA Cancer J Clin 40(3):150–165
Cèfaro GA, Genovesi D, Perez CA (2013) Delineating organs at risk in radiation therapy. Springer Verlag Italia
Cox JD et al (1995) Toxicity criteria of the radiation therapy oncology group (RTOG) and the european organization for research and treatment of cancer (EORTC). Int J Radiat Oncol Biol Phys 31(5):1341–1346
Rancati T, Schwarz M, Allen AM, Feng F, Popovtzer A, Mittal B, Eisbruch A (2010) Radiation dose-volume effects in the larynx and pharynx. Int J Radiat Oncol Biol Phys 76:S64–S69
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Sourati, A., Ameri, A., Malekzadeh, M. (2017). Laryngeal Edema. In: Acute Side Effects of Radiation Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-55950-6_9
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DOI: https://doi.org/10.1007/978-3-319-55950-6_9
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