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Contrast Coefficients Meta-analysis

Special Method for Assessing Random Effect Heterogeneity

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Abstract

Contrast coefficients are arbitrary weights given to subgroups in a study, allowing for the identification of unexpected subgroup effects. Weights should add up to unit (1), and different contrast coefficient patterns can be tested for best fit of the data. An example of four studies of 10 patients per study assessing the fall in systolic blood pressure after different treatments was used. Meta-analyses including linear contrast testing provided better data fit than did traditional fixed and random effect meta-analysis.

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  1. 1.

    More information of contrast test models and novel models have been recently published.

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© 2017 Springer International Publishing Switzerland

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Cleophas, T.J., Zwinderman, A.H. (2017). Contrast Coefficients Meta-analysis. In: Modern Meta-Analysis. Springer, Cham. https://doi.org/10.1007/978-3-319-55895-0_22

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  • DOI: https://doi.org/10.1007/978-3-319-55895-0_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-55894-3

  • Online ISBN: 978-3-319-55895-0

  • eBook Packages: MedicineMedicine (R0)

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