Abstract
The hemoglobin dissociation curve is a graphical representation of the relationship between partial pressure of oxygen (PaO2) and saturation (SaO2). The position of the curve is described by the position at which hemoglobin (Hb) is 50% saturated P50, what is normally 26.5 mmHg. A left-shifted oxyhemoglobin dissociation curve indicates a higher affinity of hemoglobin for oxygen, and this is a higher saturation at a given PaO2. The right shift of the curve indicates a lower affinity of hemoglobin and more delivery of oxygen to the tissue.
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References
Morgan GE Jr. Clinical anesthesiology. 3rd ed. New York: Lange Medical Books/McGraw-Hill Medical Publishing Division; 2002.
Collins J-A, Rudenski A, Gibson J, et al. Relating oxygen partial pressure, saturation and content: the haemoglobin-oxygen dissociation curve. Breathe. 2015;11:194–201.
Faust RJ. Anesthesiology review. 4th ed. New York: Churchill Livingston; 2014.
Linda CS. Physiology. 5th ed. Philadelphia: Saunders/Elsevier; 2014.
Suggested Reading
Lumb AB. Nunn’s applied respiratory physiology. 5th ed. Boston: Butterworth-Heinemann; 2000.
West JB. Respiratory physiology—the essentials. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2000.
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Ganta, R., Raj, T.D. (2017). Dissociation Curve. In: Raj, T. (eds) Data Interpretation in Anesthesia. Springer, Cham. https://doi.org/10.1007/978-3-319-55862-2_74
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DOI: https://doi.org/10.1007/978-3-319-55862-2_74
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