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Dissociation Curve

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Data Interpretation in Anesthesia

Abstract

The hemoglobin dissociation curve is a graphical representation of the relationship between partial pressure of oxygen (PaO2) and saturation (SaO2). The position of the curve is described by the position at which hemoglobin (Hb) is 50% saturated P50, what is normally 26.5 mmHg. A left-shifted oxyhemoglobin dissociation curve indicates a higher affinity of hemoglobin for oxygen, and this is a higher saturation at a given PaO2. The right shift of the curve indicates a lower affinity of hemoglobin and more delivery of oxygen to the tissue.

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Correspondence to Raghuvender Ganta MD, FRCA .

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Ganta, R., Raj, T.D. (2017). Dissociation Curve. In: Raj, T. (eds) Data Interpretation in Anesthesia. Springer, Cham. https://doi.org/10.1007/978-3-319-55862-2_74

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  • DOI: https://doi.org/10.1007/978-3-319-55862-2_74

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-55861-5

  • Online ISBN: 978-3-319-55862-2

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