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Diversity and Benefits of Microorganisms from the Tropics pp 185–206Cite as

Secondary Metabolites of Endophyte Fungi: Techniques and Biotechnological Approaches

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Abstract

Actually, special attention has been given to the exploration of new sources and new bioactive compounds. The microorganisms that inhabit specific habitats are potential source of new compounds, as the endophytes that inhabit the interior of plants without causing damage of host plant. This interaction needs the establishment of a chemical and genetic balance of the microbiome and host plant. Consequently, this interaction can generate new compounds of biotechnological interest. The problems of these studies involve the extraction, isolation, identification, and scale-up of production of specific molecules. Once these microorganisms are adapted to specific community and competition habitat, the axenic cultivation can alter the metabolism after the successive laboratory multiplication of these in artificial medium. This is one of the major problems to apply the endophytes on industrial chemical production. This chapter will discuss about the endophytic interaction with host plant, their capacity to produce bioactive compounds, and strategies to explore this potential.

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  1. Laboratory of Microbial Biotechnology – LBIOMIC, Department of Biotechnology, Genetic and Cell Biology, Center of Biological Sciences, State University of Maringá, Av. Colombo, 5790, Jd. Universitário, Maringá, PR, 87020-900, Brazil

    João Alencar Pamphile, Marcos Alessandro dos Santos Ribeiro & Julio Cesar Polonio

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  1. João Alencar Pamphile
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Correspondence to João Alencar Pamphile .

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  1. College of Agriculture “Luiz de Queiroz”, University of São Paulo (ESALQ/USP), Piracicaba, Brazil

    João Lucio de Azevedo

  2. College of Agriculture “Luiz de Queiroz”, University of São Paulo (ESALQ/USP), Piracicaba, Brazil

    Maria Carolina Quecine

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Pamphile, J.A., dos Santos Ribeiro, M.A., Polonio, J.C. (2017). Secondary Metabolites of Endophyte Fungi: Techniques and Biotechnological Approaches. In: de Azevedo, J., Quecine, M. (eds) Diversity and Benefits of Microorganisms from the Tropics . Springer, Cham. https://doi.org/10.1007/978-3-319-55804-2_9

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