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New Advances in Stem Cell Therapy for Diabetes Mellitus

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Pancreas, Kidney and Skin Regeneration

Part of the book series: Stem Cells in Clinical Applications ((SCCA))

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Abstract

Intense research aimed to find solutions for the cure of diabetes mellitus, based on stem cell therapy to replace hypoglycemic drug or insulin administration, has been conducted over the past decades. A variety of stem cells, including induced pluripotent stem cells, embryonic stem cells, or adult stem cells such as bone marrow-, adipose tissue-, and Wharton jelly-derived stem cells, have demonstrated their ability to differentiate into insulin-producing cells and secret insulin in response to high-glucose stimulation. However, achievement of the final goal for routinely clinical application of stem cell therapy is still out of reach. In this chapter, new advances in stem cell therapy for diabetes mellitus were reviewed and discussed in attempt to clarify where we are and how we may go to reach the final goal of the cure of diabetes mellitus.

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Authors and Affiliations

  1. Department of Endocrinology, Aerospace Center Hospital, Peking University Affiliate, Beijing, 100049, China

    Lei Lei

  2. Department of Medicine, Cleveland Clinic Akron General Medical Center, Akron, OH, 44307, USA

    Yuanjie Mao

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  1. Lei Lei
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  2. Yuanjie Mao
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Correspondence to Yuanjie Mao .

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Editors and Affiliations

  1. Laboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam

    Phuc Van Pham

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Lei, L., Mao, Y. (2017). New Advances in Stem Cell Therapy for Diabetes Mellitus. In: Pham, P. (eds) Pancreas, Kidney and Skin Regeneration. Stem Cells in Clinical Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-55687-1_4

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