• Alexander MeiningEmail author
  • Martin GötzEmail author


Contrast-based endoscopic cholangio- and pancreatography has become possible after the development of side-viewing duodenoscopes in conjunction with methods to cannulate the papilla in the 1970s. This was soon complemented by therapeutic interventions, starting with endoscopic sphincterotomy in 1974 (Classen and Demling 1974). Endoscopic retrograde cholangiopancreatography (ERCP) differs from many other endoscopic procedures, as its intention is usually primarily therapeutic. Diagnostic ERCP has mostly been replaced by less invasive methods such as (endoscopic) ultrasonography, computed tomography, or magnetic resonance tomography/MR cholangiopancreatography (MRCP). In contrast, therapeutic ERCP for treatment of biliary or pancreatic stones and strictures and for palliative therapy of malignant diseases has been growing rapidly.


  1. Anderson MA, Fisher L, Jain R, Evans JA, Appalaneni V, Ben-Menachem T, Cash BD, Decker GA, Early DS, Fanelli RD, Fisher DA, Fukami N, Hwang JH, Ikenberry SO, Jue TL, Khan KM, Krinsky ML, Malpas PM, Maple JT, Sharaf RN, Shergill AK, Dominitz JA. Complications of ERCP. Gastrointest Endosc. 2012;75:467–73.CrossRefPubMedGoogle Scholar
  2. Andriulli A, Loperfido S, Napolitano G, Niro G, Valvano MR, Spirito F, Pilotto A, Forlano R. Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Am J Gastroenterol. 2007;102:1781–8.CrossRefPubMedGoogle Scholar
  3. Buxbaum J, Yan A, Yeh K, Lane C, Nguyen N, Laine L. Aggressive hydration with lactated Ringer's solution reduces pancreatitis after endoscopic retrograde cholangiopancreatography. Clin Gastroenterol Hepatol. 2014;12:303.CrossRefPubMedGoogle Scholar
  4. Cahen DL, Gouma DJ, Nio Y, Rauws EA, Boermeester MA, Busch OR, Stoker J, Lameris JS, Dijkgraaf MG, Huibregtse K, Bruno MJ. Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis. N Engl J Med. 2007;356:676–84.CrossRefPubMedGoogle Scholar
  5. Chan CH, Enns RA. ERCP in the management of choledocholithiasis in pregnancy. Curr Gastroenterol Rep. 2012;14:504–10.CrossRefPubMedGoogle Scholar
  6. Chopra KB, Peters RA, O’Toole PA, Williams SG, Gimson AE, Lombard MG, Westaby D. Randomised study of endoscopic biliary endoprosthesis versus duct clearance for bileduct stones in high-risk patients. Lancet. 1996;348:791–3.CrossRefPubMedGoogle Scholar
  7. Classen M, Demling L. Endoscopic sphincterotomy of the papilla of vater and extraction of stones from the choledochal duct (author's transl). Dtsch Med Wochenschr. 1974;99:496–7.CrossRefPubMedGoogle Scholar
  8. Cotton PB. ERCP is most dangerous for people who need it least. Gastrointest Endosc. 2001;54:535–6.CrossRefPubMedGoogle Scholar
  9. Dumonceau JM, Andriulli A, Deviere J, Mariani A, Rigaux J, Baron TH, Testoni PA. European Society of Gastrointestinal Endoscopy (ESGE) guideline: prophylaxis of post-ERCP pancreatitis. Endoscopy. 2010;42:503–15.CrossRefPubMedGoogle Scholar
  10. Elmunzer BJ, Scheiman JM, Lehman GA, Chak A, Mosler P, Higgins PD, Hayward RA, Romagnuolo J, Elta GH, Sherman S, Waljee AK, Repaka A, Atkinson MR, Cote GA, Kwon RS, McHenry L, Piraka CR, Wamsteker EJ, Watkins JL, Korsnes SJ, Schmidt SE, Turner SM, Nicholson S, Fogel EL. A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis. N Engl J Med. 2012;366:1414–22.CrossRefPubMedPubMedCentralGoogle Scholar
  11. Mazaki T, Mado K, Masuda H, Shiono M. Prophylactic pancreatic stent placement and post-ERCP pancreatitis: an updated meta-analysis. J Gastroenterol. 2013;49:343.CrossRefPubMedGoogle Scholar
  12. Neoptolemos JP, Carr-Locke DL, London NJ, Bailey IA, James D, Fossard DP. Controlled trial of urgent endoscopic retrograde cholangiopancreatography and endoscopic sphincterotomy versus conservative treatment for acute pancreatitis due to gallstones. Lancet. 1988;2:979–83.CrossRefPubMedGoogle Scholar
  13. Rosien U, Gaus A, Jung M. Recommendations for antibiotic prophylaxis in gastrointestinal endoscopy. Z Gastroenterol. 2011;49:1493–9.CrossRefPubMedGoogle Scholar
  14. Tse F, Yuan Y, Moayyedi P, Leontiadis GI. Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Cochrane Database Syst Rev. 2012;12:CD009662.PubMedGoogle Scholar
  15. van der Gaag NA, Rauws EA, van Eijck CH, Bruno MJ, van der Harst E, Kubben FJ, Gerritsen JJ, Greve JW, Gerhards MF, de Hingh IH, Klinkenbijl JH, Nio CY, de Castro SM, Busch OR, van Gulik TM, Bossuyt PM, Gouma DJ. Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med. 2010;362:129–37.Google Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Innere Medizin 1, Universitätsklinikum TübingenTübingenGermany

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