Abstract
This chapter will discuss corneal surgery in children, focusing on how to modify surgical techniques for pediatric patients. Indications for surgery, surgical techniques, and postoperative care will be discussed for surgeries including variations of keratoplasty, (penetrating, anterior lamellar, and endothelial), keratoprosthesis surgery, and ocular surface reconstruction. Ophthalmologists who diagnose, surgically manage, and care for children with corneal eye disease are rare and published treatment guidelines for pediatric corneal surgery are even rarer.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Aasuri MK, Garg P, Gokhle N, Gupta S (2000) Penetrating keratoplasty in children. Cornea 19(2):140–144
Akpek EK, Aldave AJ, Aquavella JV (2012) The use of precut, γ-irradiated corneal lenticules in Boston type 1 keratoprosthesis implantation. Am J Ophthalmol 154(3):495–498
Al-Ghamdi A, Al-Rajhi A, Wagoner MD (2007) Primary pediatric keratoplasty: indications, graft survival, and visual outcome. J AAPOS 11:41–47
Al-Torbak AA (2004) Outcome of combined Ahmed glaucoma valve implant and penetrating keratoplasty in refractory congenital glaucoma with corneal opacity. Cornea 23:554–559
Aquavella JV, Gearinger MD, Akpek EK et al (2007) Pediatric keratoprosthesis. Ophthalmology 114:989–994
Ashar JN, Madhavi Latha K, Vaddavalli PK (2012) Descemet’s stripping endothelial keratoplasty (DSEK) for children with congenital hereditary endothelial dystrophy: surgical challenges and 1-year outcomes. Graefes Arch Clin Exp Ophthalmol 250(9):1341–1345
Ashar JN, Pahuja S, Ramappa M et al (2013a) Deep anterior lamellar keratoplasty in children. Am J Ophthalmol 155(3):570–574
Ashar JN, Ramappa M, Vaddavalli PK (2013b) Paired-eye comparison of Descemet’s stripping endothelial keratoplasty and penetrating keratoplasty in children with congenital hereditary endothelial dystrophy. Br J Ophthalmol 97(10):1247–1249
Asoklis RS, Damijonaityte A, Butkiene L et al (2011) Ocular surface reconstruction using amniotic membrane following excision of conjunctival and limbal tumors. Eur J Ophthalmol 21:552–558
Dana MR, Moyes AL, Gomes JAP et al (1995) The indications for and outcome in pediatric keratoplasty. A multicenter study. Ophthalmology 102:1129–1138
Fernandez MM, Buckley EG, Afshari NA (2008) Descemet stripping automated endothelial keratoplasty in a child. J AAPOS 12:314–316
Fu Y, Gregory DG, Sippel KC, Bouchard CS, Tseng SCG (2010) The ophthalmologist’s role in the management of acute Stevens-Johnson syndrome and toxic epidermal necrolysis. The Ocular Surface 8:193–203
Ganekal S, Gangangouda C, Dorairaj S et al (2011) Early outcomes of primary pediatric keratoplasty in patients with acquired, atraumatic corneal pathology. J AAPOS 15:353–355
Golubovic S, Latkovic Z, Horvatic-obradovic M (1995) Surgical treatment of large corneal dermoid. Doc Ophthalmol 91:25–32
Gonnermann J, Klamann MK, Maier AK, Bertelmann E, Schroeter J, von Au K, Joussen AM, Torun N (2014) Descemet membrane endothelial keratoplasty in a child with corneal endothelial dysfunction in Kearns-Sayre syndrome. Cornea 33(11):1232–1234
Gregory DG (2008) The ophthalmologic management of acute Stevens-Johnson syndrome. The Ocular Surface 6:87–95
Gregory DG (2011) Treatment of acute Stevens-Johnson syndrome and toxic epidermal necrolysis using amniotic membrane: a review of 10 consecutive cases. Ophthalmology 118:908–914
Hamzaoglu EC, Straiko MD, Mayko ZM, Sáles CS, Terry MA (2015) The first 100 eyes of standardized descemet stripping automated endothelial keratoplasty versus standardized descemet membrane endothelial keratoplasty. Ophthalmology 122(11):2193–2199
Harding SA, Nischal KK, Upponi-Patil A et al (2010) Indications and outcomes of deep anterior lamellar keratoplasty in children. Ophthalmology 117:2191–2195
Hashemi H, Asghari H, Amanzadeh K, Behrooz MJ, Beheshtnejad A, Mohammadpour M (2012) Descemet stripping automated endothelial keratoplasty performed by cornea fellows. Cornea 31(9):974–977
Hong JX, Xu JJ, Sheng MJ et al (2008) Pediatric penetrating keratoplasty in Shanghai: a retrospective multiple centre study from 2003 to 2007. Chin Med J 121(19):1911–1914
Huang C, O’Hara M, Mannis MJ (2009) Primary pediatric keratoplasty: indications and outcomes. Cornea 28:1003–1008
Jeng BH, Marcotty A, Traboulsi EI (2008) Descemet stripping automated endothelial keratoplasty in a 2-year-old child. J AAPOS 12:317–318
Kang JJ, De La Cruz J, Cortina MS (2012) Visual outcomes of Boston keratoprosthesis implantation as the primary penetrating corneal procedure. Cornea, 1–5
Karadag R, Chan TCY, Azari AA et al (2016) Survival of primary penetrating keratoplasty in children. Am J Ophthalmol
Kymionis GD, Kankariya VP, Diakonis VF, Karavitaki AE, Siganos CS, Pallikaris IG (2012) Descemet stripping automated endothelial keratoplasty in a child after failed penetrating keratoplasty. J AAPOS 16(1):95–96
Lang SJ, Böhringer D, Reinhard T (2014) Surgical management of corneal limbal dermoids: retrospective study of different techniques and use of Mitomycin C. Eye (Lond) 28(7):857–862
Low JR, Anshu A, Tan ACS et al (2014) The outcomes of primary pediatric keratoplasty in Singapore. Am J Ophthalmol 158:496–502
Lowe MT, Keane MC, Coster DJ et al (2011) The outcome of corneal transplantation in infants, children, and adolescents. Ophthalmology 118:492–497
Madi S, Santorum P, Busin M (2012) Descemet stripping automated endothelial keratoplasty in pediatric age group. Saudi Journal of Ophthalmology 26:309–313
McClellan K, Lai T, Grigg J et al (2003) Penetrating keratoplasty in children: visual and graft outcome. Br J Ophthalmol 87:1212–1214
Nischal KK (2015) Genetics of congenital corneal opacification-impact on diagnosis and treatment. Cornea 34(Suppl 10):S24–S34
Patel HY, Ormonde S, Brookes NH et al (2005) The indications and outcome of paediatric corneal transplantation in New Zealand: 1991–2003. Br J Ophthalmol 89:404–408
Pirouzian A (2013) Management of pediatric corneal limbal dermoids. Clin Ophthalmol 7:607–614
Ramappa M, Ashar J, Vaddavalli PK et al (2012) Endothelial keratoplasty in children: surgical challenges and early outcomes. Br J Ophthalmol 96:1149–1151
Reinhart WJ, Musch DC, Jacobs DS, Lee WB, Kaufman SC, Shtein RM (2011) Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty a report by the American academy of ophthalmology. Ophthalmology 118(1): 209–218
Sarnicola V, Toro P, Gentile D, Hannush SB (2010) Descemetic DALK and predescemetic DALK: outcomes in 236 cases of keratoconus. Cornea. 29(1):53–59
Sayegh RR, Ang LPK, Foster CS, Dohlman CH (2008) The Boston keratoprosthesis in Stevens-Johnson syndrome. Am J Ophthalmol 145:438–444
Sejpal K, Yu F, Aldave AJ (2011) The Boston keratoprosthesis in the management of corneal limbal stem cell deficiency. Cornea 30:1187–1194
Shay E, Kheirkhah A, Liang L, Sheha H, Gregory DG, Tseng SCG (2009) Amniotic membrane transplantation as a new therapy for the acute ocular manifestations of Stevens-Johnson syndrome and toxic epidermal necrolysis. Surv Ophthalmol 54:686–696
Traish AS, Chodosh J (2010) Expanding application of the Boston type I keratoprosthesis due to advances in design and improved post-operative therapeutic strategies. Seminars in Ophthalmology 25:239–243
Vanathi M, Panda A, Vengayil S et al (2009) Major review: Pediatric keratoplasty. Surv Ophthalmol 54:245–271
Yang LLH, Lambert SR, Drews-Botsch C et al (2009) Long-term visual outcome of penetrating keratoplasty in infants and children with Peters anomaly. J AAPOS 13:175–180
Compliance with Ethical Requirements
Christina Prescott and Kathryn Colby declare that they have no conflict of interest. No human or animal studies were performed by the authors for this chapter.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Electronic Supplementary Material
Below is the link to the electronic supplementary material.
324108_1_En_8_MOESM1_ESM.mp4
Supplementary material 1 (MP4 102595 kb)
Supplementary material 2 (MP4 306757 kb)
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Prescott, C.R., Colby, K. (2017). Corneal Diseases in Children: Surgery. In: Colby, K. (eds) Corneal Diseases in Children. Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-55298-9_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-55298-9_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-55296-5
Online ISBN: 978-3-319-55298-9
eBook Packages: MedicineMedicine (R0)