Abstract
Orthogonal designs for factors with two levels can be fit using least squares. The orthogonality of the contrasts allows each coefficient to be estimated independently of the other variables in the model.
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References
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Olive, D.J. (2017). Orthogonal Designs. In: Linear Regression. Springer, Cham. https://doi.org/10.1007/978-3-319-55252-1_8
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DOI: https://doi.org/10.1007/978-3-319-55252-1_8
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