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Multi-site Measurements of Muscle O2 Dynamics During Cycling Exercise in Early Post-myocardial Infarction

  • Shun TakagiEmail author
  • Ryotaro Kime
  • Norio Murase
  • Masatsugu Niwayama
  • Takuya Osada
  • Toshihito Katsumura
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 977)

Abstract

The aim of this study was to compare the muscle oxygen dynamics between early post-myocardial infarction (n = 12; MI) and age-matched elderly subjects without MI (n = 12; CON) in several leg muscles during ramp cycling exercise. Muscle oxygen saturation (SmO2), deoxygenated-hemoglobin concentration (∆deoxy-Hb), and total-hemoglobin concentration (∆total-Hb) were monitored continuously at the distal site of vastus lateralis (VLd), proximal site of the vastus lateralis (VLp), rectus femoris (RF), vastus medialis (VM), gastrocnemius medialis (GM), and tibialis anterior (TA) muscles by near infrared spatial resolved spectroscopy. At given absolute workloads, higher SmO2 was observed at VLd, VLp, RF, and VM in MI, compared to CON. Simultaneously, in MI, deoxy-Hb was lower at VLd, VLp, and VM than CON. In contrast to the thigh muscles, muscle oxygen dynamics were similar between groups in GM and TA. In total-Hb, no significant differences were found at any measurement sites. These results demonstrated that the absence of muscle deoxygenation was observed in MI muscles, especially in the thigh muscles, but not in the lower leg muscles.

Keywords

Cycling exercise Ischemic heart disease Muscle O2 dynamics Near infrared spectroscopy Regional difference 

Notes

Acknowledgments

The authors are grateful for revision of this manuscript by Andrea Hope. This study was supported in part by Grant-in-Aid for scientific research from Japan Society for the Promotion of Science (16K16487) to S.T.

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Shun Takagi
    • 1
    • 2
    • 3
    Email author
  • Ryotaro Kime
    • 3
  • Norio Murase
    • 3
  • Masatsugu Niwayama
    • 4
  • Takuya Osada
    • 3
  • Toshihito Katsumura
    • 3
  1. 1.Faculty of Health and Sports ScienceDoshisha UniversityKyotanabeJapan
  2. 2.Faculty of Sport SciencesWaseda UniversityTokorozawaJapan
  3. 3.Department of Sports Medicine for Health PromotionTokyo Medical UniversityShinjukuJapan
  4. 4.Department of Electrical and Electronic EngineeringShizuoka UniversityHamamatsuJapan

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