In Vivo EPR Resolution Enhancement Using Techniques Known from Quantum Computing Spin Technology

  • Robabeh RahimiEmail author
  • Howard J. Halpern
  • Takeji Takui
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 977)


A crucial issue with in vivo biological/medical EPR is its low signal-to-noise ratio, giving rise to the low spectroscopic resolution. We propose quantum hyperpolarization techniques based on ‘Heat Bath Algorithmic Cooling’, allowing possible approaches for improving the resolution in magnetic resonance spectroscopy and imaging.


In vivo EPRQuantum computingHeat bath algorithmic cooling 



RR would like to thank Guanru Feng, the Institute for Quantum Computing, University of Waterloo, ON, for helpful discussions and drawing attention to the simulation results of the previous joint works. Supported by NIH grants P41 EB002034 and R01 CA98575.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Robabeh Rahimi
    • 1
    • 2
    Email author
  • Howard J. Halpern
    • 2
  • Takeji Takui
    • 3
  1. 1.Department of Radiation OncologyUniversity of Miami Miller School of MedicineMiamiUSA
  2. 2.Department of Radiation and Cellular OncologyUniversity of ChicagoChicagoUSA
  3. 3.Department of Chemistry and Molecular Materials ScienceGraduate School of Science, Osaka City UniversityOsakaJapan

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