Near-infrared spectroscopy (NIRS) can measure cortical activity during gross motor tasks based on the cerebral hemodynamic response. Although some reports suggest that cycling exercise improves cortical oxygenation, its after-effects are unknown. We examined the after-effects of low- and moderate-intensity cycling exercise on cortical oxygenation. Ten healthy volunteers (mean age 21.3 ± 0.7 years; 4 women) underwent cycle ergometer exercise at 30% or 50% of VO2peak for 20 min, followed by an 8-min post-exercise rest (PER). O2Hb levels of the supplementary motor area (SMA) and sensorimotor cortex (SMC) were recorded using a near-infrared spectroscopy system. Skin blood flow (SBF) and mean arterial pressure (MAP) were continuously measured. The peak values of O2Hb between exercise and PER were compared. The O2Hb, SBF, and MAP increased in the exercise phase. SBF degraded over time, and MAP decreased immediately after exercise. The O2Hb decreased immediately and increased again in the PER. There were no significant differences between exercise and PER in the SMC in the 30% VO2peak experiment or in the SMA and SMC in the 50% VO2peak experiment. The O2Hb in the motor-related area was elevated during both exercise and PER especially in the 50% VO2peak experiment.
Cortical oxyhemoglobin Cycling exercise Moderate-intensity Motor-related area After-effects
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This study was supported by a Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science and a Grant-in-Aid for Exploratory Research from the Niigata University of Health and Welfare.
Boas DA, Gaudette T, Strangman G et al (2001) The accuracy of near infrared spectroscopy and imaging during focal changes in cerebral hemodynamics. NeuroImage 13:76–90CrossRefPubMedGoogle Scholar
Miyai I, Tanabe HC, Sase I et al (2001) Cortical mapping of gait in humans: A near-infrared spectroscopic topography study. NeuroImage 14:1186–1192CrossRefPubMedGoogle Scholar
Bhambhani Y, Malik R, Mookerjee S (2007) Cerebral oxygenation declines at exercise intensities above the respiratory compensation threshold. Respir Physiol Neurobiol 156:196–202CrossRefPubMedGoogle Scholar
Rupp T, Perrey S (2008) Prefrontal cortex oxygenation and neuromuscular responses to exhaustive exercise. Eur J Appl Physiol 102:153–163PubMedGoogle Scholar
Anazodo UC, Shoemaker JK, Suskin N et al (2013) An investigation of changes in regional gray matter volume in cardiovascular disease patients, pre and post cardiovascular rehabilitation. Neuroimage Clin 3:388–395CrossRefPubMedPubMedCentralGoogle Scholar
Tsubaki A, Takai H, Kojima S et al (2016) Changes in cortical oxyhaemoglobin signal during low-intensity cycle ergometer activity: a near-infrared spectroscopy study. Adv Exp Med Biol 876:79–85CrossRefPubMedGoogle Scholar
Tamura M, Hoshi Y, Okada F (1997) Localized near-infrared spectroscopy and functional optical imaging of brain activity. Philos Trans R Soc Lond Ser B Biol Sci 352:737–742CrossRefGoogle Scholar
Peltonen JE, Paterson DH, Shoemaker JK et al (2009) Cerebral and muscle deoxygenation, hypoxic ventilatory chemosensitivity and cerebrovascular responsiveness during incremental exercise. Respir Physiol Neurobiol 169:24–35CrossRefPubMedGoogle Scholar
Higashimoto Y, Honda N, Yamagata T et al (2011) Activation of the prefrontal cortex is associated with exertional dyspnea in chronic obstructive pulmonary disease. Respiration 82:492–500CrossRefPubMedGoogle Scholar
Takahashi T, Takikawa Y, Kawagoe R et al (2011) Influence of skin blood flow on near-infrared spectroscopy signals measured on the forehead during a verbal fluency task. NeuroImage 57:991–1002CrossRefPubMedGoogle Scholar
Minati L, Kress IU, Visani E et al (2011) Intra- and extra-cranial effects of transient blood pressure changes on brain near-infrared spectroscopy (NIRS) measurements. J Neurosci Methods 197:283–288CrossRefPubMedPubMedCentralGoogle Scholar
Tsubaki A, Takai H, Oyanagi K et al (2016) Correlation between the cerebral oxyhaemoglobin signal and physiological signals during cycling exercise: A near-infrared spectroscopy study. Adv Exp Med Biol 923:159–166CrossRefPubMedGoogle Scholar
Sato K, Ogoh S, Hirasawa A et al (2011) The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans. J Physiol 589:2847–2856CrossRefPubMedPubMedCentralGoogle Scholar
Frangos JA, Eskin SG, Mcintire LV et al (1985) Flow effects on prostacyclin production by cultured human endothelial cells. Science 227:1477–1479CrossRefPubMedGoogle Scholar
Dimmeler S, Fleming I, Fisslthaler B et al (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601–605CrossRefPubMedGoogle Scholar
Obrig H, Wolf T, Doge C et al (1996) Cerebral oxygenation changes during motor and somatosensory stimulation in humans, as measured by near-infrared spectroscopy. Adv Exp Med Biol 388:219–224CrossRefPubMedGoogle Scholar
Niederhauser BD, Rosenbaum BP, Gore JC et al (2008) A functional near-infrared spectroscopy study to detect activation of somatosensory cortex by peripheral nerve stimulation. Neurocrit Care 9:31–36CrossRefPubMedGoogle Scholar