Abstract
The present study investigated whether changes in oxyhemoglobin (O2Hb) concentration over time differed across brain regions according to differences in gross movement intensity. Thirteen healthy adults (21.2 ± 1.0 years, 8 women) participated in this study. After 180 s of rest, the participants performed 600 s of exercise on a cycle ergometer. Exercise intensity was set at 30%VO2peak and 50%VO2peak. The prefrontal cortex (PFC) and primary motor cortex (M1) were chosen as regions of interest. In addition, mean arterial pressure (MAP) and scalp blood flow (SBF) were measured simultaneously. O2Hb concentration in PFC and M1 was significantly decreased in initial phase of the exercise, while it was significantly increased from the mid to final phase for both intensities compared with resting state values (p < 0.01). The O2Hb concentrations in the PFC and M1 were significantly decreased in the initial exercise phase. However, the MAP and SBF values did not exhibit a similar pattern. The main findings of our study were the follows: (1) During cycle ergometer exercise at the 30% and 50% O2Hb peak, the after O2Hb concentrations were transiently decreased in the initial exercise phase, and the concentrations then steadily increased in both the PFC and M1; and (2) the duration of the transient decreases in the O2Hb concentrations varied according to the brain region and exercise intensity.
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References
Jobsis FF (1977) Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 23:1264–1267
Endo K, Matsukawa K, Liang N et al (2013) Dynamic exercise improves cognitive function in association with increased prefrontal oxygenation. J Physiol Sci 63(4):287–298
Giles GE, Brunyé TT, Eddy MD et al (2014) Acute exercise increases oxygenated and deoxygenated hemoglobin in the prefrontal cortex. Neuroreport 25:1320–1325
Timinkul A, Kato M, Omori T et al (2008) Enhancing effect of cerebral blood volume by mild exercise in healthy young men: A near-infrared spectroscopy study. Neurosci Res 61:242–248
Bediz CS, Oniz A, Guducu C et al (2016) Acute supramaximal exercise increases the brain oxygenation in relation to cognitive workload. Front Hum Neurosci 10:174
Suzuki M, Miyai I, Ono T et al (2004) Prefrontal and premotor cortices are involved in adapting walking and running speed on the treadmill: an optical imaging study. NeuroImage 23:1020–1026
Sato T, Ito M, Suto T et al (2007) Time courses of brain activation and their implications for function: a multichannel near-infrared spectroscopy study during finger tapping. Neurosci Res 58:297–304
Minati L, Kress IU, Visani E et al (2011) Intra- and extra-cranial effects of transient blood pressure changes on brain near-infrared spectroscopy (NIRS) measurements. J Neurosci Methods 197:283–288
Miyazawa T, Horiuchi M, Komine H et al (2013) Skin blood flow influences cerebral oxygenation measured by near-infrared spectroscopy during dynamic exercise. Eur J Appl Physiol 113:2841–2848
Hirasawa A, Yanagisawa S, Tanaka N et al (2015) Influence of skin blood flow and source-detector distance on near-infrared spectroscopy-determined cerebral oxygenation in humans. Clin Physiol Funct Imaging 35:237–244
Fox PT, Raichle ME, Mintun MA et al (1988) Nonoxidative glucose consumption during focal physiologic neural activity. Science 241:462–464
Bandettini P, Wong EC, Hinks RS et al (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25:390–397
Taoka T, Iwasaki S, Uchida H et al (1998) Age correlation of the time lag in signal change on EPI-fMRI. J Comput Assist Tomogr 22:514–517
Sato K, Ogoh S, Hirasawa A et al (2011) The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans. J Physiol 589:2847–2856
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Takehara, N. et al. (2017). Changes in Oxyhemoglobin Concentration in the Prefrontal Cortex and Primary Motor Cortex During Low- and Moderate-Intensity Exercise on a Cycle Ergometer. In: Halpern, H., LaManna, J., Harrison, D., Epel, B. (eds) Oxygen Transport to Tissue XXXIX. Advances in Experimental Medicine and Biology, vol 977. Springer, Cham. https://doi.org/10.1007/978-3-319-55231-6_33
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DOI: https://doi.org/10.1007/978-3-319-55231-6_33
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