Abstract
It is now well established that carotid bodies are sensory organs for monitoring arterial blood oxygen levels and trigger reflexes that are critical for maintaining homeostasis during hypoxemia. This review article provides a brief account of the early studies leading to the discovery of the carotid body as a sensory receptor and addresses current views of O2 sensing mechanism(s) in the carotid body and their physiological importance.
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Acknowledgments
The research in our laboratory is supported by grants from National Institutes of Health, Heart, Lung and Blood Institute PO1-HL-90554 and UH2-HL-123610.
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Prabhakar, N.R., Peng, YJ. (2017). Oxygen Sensing by the Carotid Body: Past and Present. In: Halpern, H., LaManna, J., Harrison, D., Epel, B. (eds) Oxygen Transport to Tissue XXXIX. Advances in Experimental Medicine and Biology, vol 977. Springer, Cham. https://doi.org/10.1007/978-3-319-55231-6_1
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DOI: https://doi.org/10.1007/978-3-319-55231-6_1
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