Abstract
This chapter presents the case of a premature (31-week gestation) infant whose birth weight was 1.4 kg and who did well for the first 49 days of life. On day of life 50, the infant developed signs of sepsis and was found to have intestinal volvulus with perforation that quickly progressed to multiple organ failure, including acute kidney injury (AKI) with fluid overload. The chapter reviews the current diagnostic criteria for neonatal AKI while addressing the decision to launch renal replacement therapy. The choice of continuous renal replacement therapy (CRRT) as the RRT modality of choice for this infant is examined, followed by an in-depth discussion of the major technical issues encountered when providing CRRT for any neonate, including vascular access, blood vs. saline circuit prime, and anticoagulation modality. The details of the CRRT prescription chosen for this infant are reviewed. The chapter concludes with a summary of the infant’s course on CRRT and a series of clinical pearls illustrated by the case.
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Askenazi, D.J. (2017). Continuous Renal Replacement Therapy (CRRT) for a Neonate. In: Warady, B., Schaefer, F., Alexander, S. (eds) Pediatric Dialysis Case Studies. Springer, Cham. https://doi.org/10.1007/978-3-319-55147-0_37
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DOI: https://doi.org/10.1007/978-3-319-55147-0_37
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