Abstract
Children on long-term maintenance dialysis have significantly diminished life expectancy mostly due to cardiovascular disease. In children, cardiac arrest is the most common cause of death, while in adults with childhood onset of ESRD, accelerated and premature coronary artery disease and cardiomyopathy are major causes of cardiac death. Cardiac and vascular abnormalities develop early in the course of chronic kidney disease (CKD) in children and reach a peak when the child enters maintenance dialysis. This is due to an exceptionally high prevalence of traditional and uremia-related cardiovascular risk factors. Aggressive dialysis and kidney transplantation are the best options to prevent development and progression of cardiovascular disease (CVD) in children on dialysis.
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Mitsnefes, M.M. (2017). Cardiovascular Disease. In: Warady, B., Schaefer, F., Alexander, S. (eds) Pediatric Dialysis Case Studies. Springer, Cham. https://doi.org/10.1007/978-3-319-55147-0_27
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DOI: https://doi.org/10.1007/978-3-319-55147-0_27
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