Abstract
Computational modeling and simulation studies involving human spine using finite element methods typically encompass fixed geometry and material properties. The accuracy and reliability of the response obtained from these simulations are largely influenced by the input data from human spine. Input data uncertainties associated with natural variations in geometry and material characteristics of the human spine cause response to be imprecise. In addition if human is a pediatric human, growth rate uncertainties influence the predictions and their validations against experimental findings. The end result is the uncertainties in computationally predicted response. Some prediction uncertainties can be reduced by additional data collection and characterization. This paper presents a unique in-vivo noninvasive method and characterizes geometry and growth rate of human spine. The results will serve useful in reducing prediction uncertainties in finite element simulations of human spine. This study is the first extensive study of the pediatric spinal structure dimensions to include such a large variety of bony structures for this particular age group.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lopez, I., Sarigul-Klijn, N.: Effects of dimensional reduction techniques on structural damage assessment under uncertainty. ASME. J. Vib. Acoust. 133(6), 061008–061008-12 (2011). doi:10.1115/1.4003592
Lopez, I., Sarigul-Klijn, N.: A review of uncertainty in flight vehicle structural damage monitoring, diagnosis and control: Challenges and opportunities. Prog. Aerosp. Sci. 46(7), 247–273 (2010)
Anderson, M., Hwang, S., Green, W.T.: Growth of the normal trunk in boys and girls during the 2nd decade of life: related to age, maturity, and ossification of the iliac epiphyses. J. Bone Joint Surg. Am. 47, 1554–1564 (1965)
Hellsing, E., Reigo, T., McWilliam, J., Spangfort, E.: Cervical and lumbar lordosis and thoracic kyphosis in 8, 11, and 15-year-old children. Euro. J. Orthod. 9, 129–138 (1987)
Knirsch, W., Keutz, C., Haffner, N., Langer, M., Kececioglu, D.: Normal values of the sagittal diameter of the lumbar spine (vertebral body and dural sac) in children measured by MRI. Pediatr. Radiol. 35, 419–424 (2005)
Lord, M.J., Ogden, J.A., Ganey, T.M.: Postnatal development of the thoracic spine. Spine. 20, 1692–1698 (1995)
Sze, G., Baierl, P., Bravo, S.: Evolution of the infant spinal column: evaluation with MR Imaging. Radiology. 181, 819–827 (1991)
Taylor, J.R.: Growth of human intervertebral discs and vertebral bodies. J. Anat. 120, 49–68 (1970)
Vara, C.S., Thompson, G.H.: A cadaveric examination of pediatric cervical pedicle morphology. Spine. 31, 1107–1112 (2006)
Wang, J.C., Nuccion, S.L., Feighan, J.E., Cohen, B., Dorey, F.J., Scoles, P.V.: Growth and development of the pediatric cervical spine documented radiographically. J. Bone Joint Surg. 83-A, 1212–1218 (2001)
Centers for Disease Control and Prevention (CDC): Spina bifida and anencephaly before and after folic acid mandate—United States, 1995–1996 and 1999–2000. MMWR Morb. Mortal. Wkly Rep. 53, 362–365 (2004)
Kasai, T., Ikata, T., Katoh, S., Miyake, R., Tsubo, M.: Growth of the cervical spine with special reference to its lordosis and mobility. Spine. 21, 2067–2073 (1996)
Kuo, Y.L., Tully, E.A., Galea, M.P.: Video analysis of sagittal spinal posture in healthy young and older adults. J. Manip. Physiol. Ther. 32, 210–215 (2009)
Papadakis, M., Papadokostakis, G., Stergiopoulos, K., Kampanis, N., Katonis, P.: Lumbar lordosis in osteoporosis and in osteoarthritis. Eur. Spine J. 18, 608–613 (2009)
Widhe, T.: Spine: posture, mobility and pain. A longitudinal study from childhood to adolescence. Eur. Spine J. 10, 118–123 (2001)
Willner, S., Johnson, B.: Thoracic kyphosis and lumbar lordosis during the growth period in children. Acta Paediatr. Scand. 72, 873–878 (1983)
Cramer, G.D.: Clinical anatomy of the spine, spinal cord, and ANS. Elsevier, St. Louis (2014)
Clark, G.A., Panjabi, M.M., Wetzel, F.T.: Can infant malnutrition cause adult vertebral stenosis? Spine. 10, 165–170 (1985)
Dimeglio, A.: Growth in pediatric orthopaedics. J. Pediatr. Orthop. 21, 549–555 (2001)
Lovell, W., Winter, R.: Lovell and Winter's Pediatric Orthopedics, 6th edn. Lippincott, Williams & Wilkins, Philadelphia (2005)
Smith, J.T.: The use of growth-sparing instrumentation in pediatric spinal deformity. Orthop. Clin. North Am. 38, 547–552 (2007)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 The Society for Experimental Mechanics, Inc.
About this paper
Cite this paper
Doughty, E.S., Sarigul-Klijn, N. (2017). Towards Reducing Prediction Uncertainties in Human Spine Finite Element Response: In-Vivo Characterization of Growth and Spine Morphology. In: Barthorpe, R., Platz, R., Lopez, I., Moaveni, B., Papadimitriou, C. (eds) Model Validation and Uncertainty Quantification, Volume 3. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, Cham. https://doi.org/10.1007/978-3-319-54858-6_32
Download citation
DOI: https://doi.org/10.1007/978-3-319-54858-6_32
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-54857-9
Online ISBN: 978-3-319-54858-6
eBook Packages: EngineeringEngineering (R0)