Radiotherapy (RT) is employed as a curative rather than palliative treatment in children with cancer. Paediatric cancers are rare, so use of positron emission tomography-computed tomography (PET-CT) to plan RT is typically performed by specialist centres. A physiologically heterogeneous population, ranging from neonate to adolescent, has practical implications for image acquisition, interpretation and RT dose. Increased susceptibility to the effects of ionising radiation leads to pronounced adverse effects, with the long-term risk of secondary malignancy amplified by concurrent chemotherapy and imaging studies performed during and after treatment .
KeywordsConcurrent Chemotherapy Paediatric Cancer Secondary Malignancy Reduce Radiation Dose Procedural Compliance
- 3.Birk Christensen CB, Loft L, Kiil Berthelsen A. PET/CT radiotherapy planning in children. In: Kinggaard MH, Federspiel P, editors. PET/CT radiotherapy planning part 3: a technologist guide. Vienna: European Association of Nuclear Medicine; 2012. p. 67–71.Google Scholar
- 10.Spehl TS, Gotz IS. PET/CT-based radiotherapy planning in brain malignancies. In: E.A.f.N. Medicine, editor. PET/CT radiotherapy planning part 3: a technologist guide. Vienna: European Association of Nuclear Medicine; 2012.Google Scholar