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Melanoma

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Part of the book series: Clinicians’ Guides to Radionuclide Hybrid Imaging ((PET/CT))

Abstract

Melanomas arise from melanocytes located on the basement membrane at the epidermal/dermal junction. The lifetime risk of melanoma has been increasing in recent decades particularly in Caucasians, which is in part due to increased diagnosis of early stage cancer [1]. Rates of melanoma around the world vary from as little as 0.2/100,000 in females in India to 55.8/100,000 in males in northern Australia [2, 3]. Ethnicity influences the rates of melanoma with higher rates in Caucasians in Australia, New Zealand and Europe and lower levels in Asians. Within the USA, there are higher rates in Caucasians, compared to Hispanic and Black communities [2, 3].

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References

  1. Welch HG, Woloshin S, Schwartz LM. Skin biopsy rates and incidence of melanoma: population based ecological study. BMJ. 2005;331(7515):481.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Bosserhoff A-K, editor. Melanoma development: molecular biology, genetics, and clinical application. New York: Springer; 2011.

    Google Scholar 

  3. International Agency for Research on Cancer (WHO), International Association of Cancer Registries. Cancer incidence in five continents. Vol. IX. Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, Boyle P, editors. IARC Scientific Publication No. 160. Lyon; 2007.

    Google Scholar 

  4. National Comprehensive Cancer Network. Melanoma: clinical practice guidelines in oncology. Version 2. National Comprehensive Cancer Network; 2007.

    Google Scholar 

  5. Balch CM, editor. Cutaneous melanoma. 5th ed. St. Louis, MO: Quality Medical Publishing; 2009.

    Google Scholar 

  6. Hansson J. Familial cutaneous melanoma. Adv Exp Med Biol. 2010;685:134–45.

    Article  CAS  PubMed  Google Scholar 

  7. Psaty EL, Scope A, Halpern AC, Marghoob AA. Defining the patient at high risk for melanoma. Int J Dermatol. 2010;49:362–76.

    Article  PubMed  Google Scholar 

  8. Cockerell C, Mihm CM, Hall BJ, Chisholm C, Jessup C, Merola M, editors. Dermatopathology-clinicopathological correlations. London: Springer-Verlag; 2014.

    Google Scholar 

  9. Rigel DS, Carucci JA. Malignant melanoma: prevention, early detection and treatment in the 21st century. CA Cancer J Clin. 2000;50(4):215–36. quiz 237–40

    Article  CAS  PubMed  Google Scholar 

  10. Bastaille V, Sasieni P, Curley RK, Cook MG, Marsden RA. Melanoma yield, number of biopsies and missed melanomas in a British teaching hospital pigmented lesion clinic: a 9-year retrospective study. Br J Dermatol. 1999;140(2):243–8.

    Article  Google Scholar 

  11. Zaidi Z, editor. Dermatology in clinical practice. Dordrecht: Springer; 2010.

    Google Scholar 

  12. SIGN Guideline no. 72. Cutaneous melanoma: a national clinical guideline. Updated February 2004. Scottish Intercollegiate Guidelines Network; 2003.

    Google Scholar 

  13. National Comprehensive Cancer Network. Melanoma: clinical practice guidelines in oncology. Version 2. National Comprehensive Cancer Network; 2007.

    Google Scholar 

  14. Cohen LM. Lentigo maligna and lentigo maligna melanoma. J Am Acad Dermatol. 1995;33(6):923–36. quiz 937–40. Review

    Article  CAS  PubMed  Google Scholar 

  15. McKenna JK, Florell SR, Goldman GD, Bowen GM. Lentigo maligna/lentigo maligna melanoma: current state of diagnosis and treatment. Dermatol Surg. 2006;32(4):493–504.

    CAS  PubMed  Google Scholar 

  16. Quinn MJ, Crotty KA, Thompson JF, Coates AS, O’Brien CJ, McCarthy WH. Desmoplastic and desmoplastic neurotropic melanoma: experience with 280 patients. Cancer. 1998;83(6):1128–35.

    Article  CAS  PubMed  Google Scholar 

  17. Carlson JA, Dickersin GR, Sober AJ, Barnhill RL. Desmoplastic neurotropic melanoma. A clinicopathologic analysis of 28 cases. Cancer. 1995;75(2):478–94.

    Article  CAS  PubMed  Google Scholar 

  18. Phan A, Touzet S, Dalle S, Ronger-Savlé S, Balme B, Thomas L. Acral lentiginous melanoma: histopathological prognostic features of 121 cases. Br J Dermatol. 2007;157(2):311–8.

    Article  CAS  PubMed  Google Scholar 

  19. Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol. 2009;27(36):6199–206.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Spillane JB, Henderson MA. Improving care for patients with melanoma. ANZ J Surg. 2012;82(1–2):3–5.

    Article  PubMed  Google Scholar 

  21. Balch CM, Gershenwald JE, Soong SJ, Thompson JF. Update on the melanoma staging system: the importance of sentinel node staging and primary tumour mitotic rate. J Surg Oncol. 2011;104(4):379–85.

    Article  PubMed  Google Scholar 

  22. Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, Sullivan DC, Jessup JM, Brierley JD, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR (Eds). AJCC Cancer Staging Manual, 8th Edition, Springer. 2017.

    Google Scholar 

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Correspondence to John Spillane .

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Spillane, J., Henderson, M., McArthur, G.A. (2017). Melanoma. In: Hofman, M., Hicks, R. (eds) PET/CT in Melanoma. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-319-54741-1_1

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  • DOI: https://doi.org/10.1007/978-3-319-54741-1_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-54740-4

  • Online ISBN: 978-3-319-54741-1

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