Abstract
It is now well known that the brain is electrically excitable. Physicians frequently make use of electromagnetic properties to monitor or localize brain functions in patients (e.g. EEG, MRI or electrical stimulation of the brain). However, in the nineteenth century, it was accepted as a fact that the cerebral hemispheres were non-excitable ‘by all common psychologic stimuli’ [1]. This dogma prevailed to such an extent that studies that challenged this concept initially had to be performed outside of the universities [2].
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- 1.
See Young (1970) for details of this dispute [9].
- 2.
Grunbaum changed his name into Leyton in 1915.
- 3.
Quotation taken from Devinsky (1993) [21]
- 4.
The Wada test cannot specify laterality of all language functions, in particular functions that are classically attributed to the postero-temporal and infero-parietal region (such as verbal comprehension) [139]. Possibly, these regions are spared after injection of sodium amytal.
References
Fritsch GT, Hitzig E. Über die elektrische Erregbarkeit des Grosshirns. Arch Anat Phys. 1870;37:300–32.
Carlson C, Devinsky O. The excitable cerebral cortex Fritsch G, Hitzig E. Uber die elektrische Erregbarkeit des Grosshirns. Arch Anat Physiol Wissen 1870;37:300–32. Epilepsy Behav. 2009;15:131–2.
Gross CG. The discovery of motor cortex and its background. J Hist Neurosci. 2007;16:320–31.
Boling W, Olivier A, Fabinyi G. Historical contributions to the modern understanding of function in the central area. Neurosurgery. 2002;50:1296–309; discussion 1309.
Aldini G. An account of the late improvements in galvanism with a series of curious and interesting experiments. London: Cuthell and Martin; 1803.
Ferrier D. The functions of the brain. New York: GP Putnam’s Sons; 1886.
Withington ET. Hippocrates: on wounds in the head, vol. 3. Cambridge: Harvard University Press; 1927.
Finger S. Origins of neuroscience: a history of explorations into brain function. New York: Oxford University Press; 2001.
Young RM. Mind, brain and adaptation in the nineteenth century. New York: Oxford University Press; 1970.
Jefferson G. Selected papers. London: Pitman; 1960.
Jackson JH. Notes on the physiology and pathology of the nervous system. Med Times Gaz. 1868;2:696.
York GK, Steinberg DA. Hughlings Jackson’s neurological ideas. Brain. 2011;134:3106–13.
Sherrington CS. Sir David Ferrier (1843-1928). London: Oxford University Press; 1937. p. 302.
Horsley V. The Linacre Lecture on the function of the so-called motor area of the brain: delivered to the Master and Fellows of St. John’s College, Cambridge, May 6th, 1909. Br Med J. 1909;2:121.
Grünbaum ASF, Sherrington CS. Observations on the physiology of the cerebral cortex of some of the higher apes. Proc R Soc Lond. 1901;69:206–9.
Lemon RN. An enduring map of the motor cortex. Exp Physiol. 2008;93:798–802.
Archibald E. Surgical affections of the head. In: Bryant JD, Buck AH, editors. American practice of surgery. New York: William Wood and Co.; 1908. p. 3–379.
Phillips CG, Porter R. Corticospinal neurones. Their role in movement. London: Academic Press; 1977. p. 65.
Frohlich A, Sherrington CS. J Physiol. 1901;xxviii.
Leyton ASF, Sherrington CS. Observations on the excitable cortex of the chimpanzee, orang-utan, and gorilla. Exp Physiol. 1917;11:135–222.
Devinsky O, Beric A, Dogali M. Electrical and magnetic stimulation of the brain and spinal cord. New York: Raven Press; 1993.
Sanes JN, Schieber MH. Orderly somatotopy in primary motor cortex: does it exist? NeuroImage. 2001;13:968–74.
Brown GT. J Physiol. 1914;xlviii:xxix, xxx, xxxiii.
Brown GT, Sherrington CS. On the instability of a cortical point. Proc R Soc London, Ser B. 1912;85:250–77.
Krause F. Chirurgie des Gehirns und Rueckenmarks; 1911.
Vilensky JA, Gilman S. Horsley was the first to use electrical stimulation of the human cerebral cortex intraoperatively. Surg Neurol. 2002;58:425–6.
Pondal-Sordo M, Diosy D, Tellez-Zenteno JF, et al. Epilepsy surgery involving the sensory-motor cortex. Brain. 2006;129:3307–14.
Krause F, Schum H. Spezielle Chirurgie der Gehirnkrankheiten; 1931.
Foerster O, Penfield WP. The structural basis of traumatic epilepsy and results of radical operation. Brain. 1930;53:99–119.
Foerster O, Altenburger H. Elektrobiologische Vorgänge an der menschlichen Hirnrinde. J Neurol. 1935;135:277–88.
Luders HO, Comair YG. Epilepsy surgery. Philadelphia: Lippincott Williams and Wilkins; 2001.
Sarikcioglu L. Otfrid Foerster (1873-1941): one of the distinguished neuroscientists of his time. J Neurol Neurosurg Psychiatry. 2007;78:650.
Penfield WP, Boldrey E. Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain. 1937;60:389–443.
Penfield WP, Rasmussen T. The cerebral cortex of man. New York: The Macmillan Company; 1957.
Feindel W. The physiologist and the neurosurgeon: the enduring influence of Charles Sherrington on the career of Wilder Penfield. Brain. 2007;130:2758–65.
Penfield WP, Roberts L. Speech and brain mechanisms. Princeton University Press: Princeton; 1959.
Catani M, Dell’acqua F, Vergani F, et al. Short frontal lobe connections of the human brain. Cortex. 2012;48:273–91.
Foerster O. Symptomatologie der Erkrankingen des Grosshirns: motorische Felder und Bahnen. In: Bumke O, Foerster O, editors. Handbuch der Neurologie. Berlin: Springer; 1936.
Luria AR. Higher cortical functions in man. 2nd ed. New York: Basic Books Inc.; 1980.
Schmahmann JD, Pandya DN. Fiber pathways of the brain. New York: OUP; 2006.
Sakamoto T, Porter LL, Asanuma H. Long-lasting potentiation of synaptic potentials in the motor cortex produced by stimulation of the sensory cortex in the cat: a basis of motor learning. Brain Res. 1987;413:360–4.
Ferezou I, Haiss F, Gentet LJ, et al. Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice. Neuron. 2007;56:907–23.
Schott GD. Penfield’s homunculus: a note on cerebral cartography. J Neurol Neurosurg Psychiatry. 1993;56:329–33.
Penfield WP. Ferrier lecture: some observations on the cerebral cortex of man. Proc R Soc London, Ser B. 1947;134:329–47.
Sanes JN, Donoghue JP. Plasticity and primary motor cortex. Annu Rev Neurosci. 2000;23:393–415.
Vargas-Irwin CE. Motor cortical control of naturalistic reachting and grasping actions [thesis]. Brown University; 2010.
Snyder PJ, Whitaker HA. Neurologic heuristics and artistic whimsy: the cerebral cartography of Wilder Penfield. J Hist Neurosci. 2013;22(3):277–91.
Bartholow R. Experimental investigations into the functions of the human brain. Am J Med Sci. 1874;67:305–13.
Harris LJ, Almerigi JB. Probing the human brain with stimulating electrodes: the story of Roberts Bartholow’s (1874) experiment on Mary Rafferty. Brain Cogn. 2009;70:92–115.
Kim OJ. Experiment at bedside: Harvey Cushing’s neurophysiological research. Korean J Med Hist. 2009;18(2):205–22.
Bliss M. Harvey Cushing: A life in surgery. New York: Oxford University Press; 2005.
Cushing H. The surgical aspects of major neuralgia of the trigeminal nerve. JAMA. 1905;44:860–5.
Miller JT, Rahimi SY, Lee M. History of infection control and its contributions to the development and success of brain tumor operations. Neurosurg Focus. 2005;18:e4.
Clark FC. A brief history of antiseptic surgery. Med Library Hist J. 1907;5:145–72.
Fodstad H, Kelly PJ, Buchfelder M. History of the Cushing reflex. Neurosurgery. 2006;59:1132–7; discussion 1137.
Jefferson G. Harvey Cushing, April 8, 1869-October 7, 1939. Surg Neurol. 1974;2:217–24.
Powell M. Sir Victor Horsley—an inspiration. BMJ. 2006;333:1317–9.
Cushing H. A note upon the faradic stimulation of the postcentral gyrus in conscious patients. Brain. 1909;32:44–53.
Pendleton C, Zaidi HA, Chaichana KL, et al. Harvey Cushing’s contributions to motor mapping: 1902-1912. Cortex. 2012;48:7–14.
Horsley V. The Linacre lecture on the function of the so-called motor area of the brain. Br Med J. 1909;2:121.
Tan TC, Black PM. The contributions of Otfrid Foerster (1873-1941) to neurology and neurosurgery. Neurosurgery. 2001;49:1231–6.
Foerster O, Penfield WP. Der Narbenzug am und im Gehirn bei traumatischer Epilepsie in seiner Bedeutung für das Zustandekommen der Anfälle und für die therapeutische Bekämpfung derselben. Z ges Neurol Psychiat. 1930;125:475–572.
Preul MC, Feindel W. Origins of Wilder Penfield’s surgical technique: the role of the “Cushing ritual” and influences from the European experience. J Neurosurg. 1991;75:812–20.
Penfield WP. Diencephalic autonomic epilepsy. Res Publ Assoc Nerv Ment Dis. 1930;9:645–63.
Nielsen JM. The possibility of pure motor aphasia. Bull Los Angel Neurol Soc. 1936;1:11–4.
Penfield WP, Jasper H. Epilepsy and the functional anatomy of the human brain. Boston: Little, Brown and Company; 1954.
Penfield W, Welch K. The supplementary motor area of the cerebral cortex: a clinical and experimental study. Arch Neurol Psychiatr. 1951;66:289.
Geschwind N. Selected papers on language and the brain. New York: Springer; 1974.
Schwab O. Über vorübergehenden aphasische Störungen nach Rindenexzision aus dem linken Stirnhirn bei Epileptikern. Dtsch Z Nervenheilk. 1927;94:117–84.
Bogen JE, Bogen GM. Wernicke’s region—where is it? Ann N Y Acad Sci. 1976;280:834–43.
Prados M, Strowger B, Feindel W. Studies on cerebral edema: I. Reaction of the brain to air exposure; pathologic changes; II. Physiologic changes. Arch Neurol Psychiatry. 1945;54:163–74. 290
Crosson B. Subcortical functions in language and memory. New York: Guilford Press; 1992.
Ford AA, Triplett W, Sudhyadhom A, et al. Broca’s area and its striatal and thalamic connections: a diffusion-MRI tractography study. Front Neuroanat. 2013;7:1–12.
Fedio P, Van Buren JM. Memory deficits during electrical stimulation of the speech cortex in conscious man. Brain Lang. 1974;1:29–42.
Ojemann GA. Cortical organization of language. J Neurosci. 1991;11:2281–7.
Lubrano V, Draper L, Roux FE. What makes surgical tumor resection feasible in Broca’s area? Insights into intraoperative brain mapping. Neurosurgery. 2010;66:868–75; discussion 875.
Thiel A, Herholz K, Koyuncu A, et al. Plasticity of language networks in patients with brain tumors: a positron emission tomography activation study. Ann Neurol. 2001;50:629.
Stern Y. Cognitive reserve. Neuropsychologia. 2009;47:2015–28.
Prince M, Acosta D, Ferri CP, et al. Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: a 10/66 Dementia Research Group population-based cohort study. Lancet. 2012;380(9836):50–8.
Ojemann GA, Whitaker HA. Language localization and variability. Brain Lang. 1978;6:239–60.
Rutten GJ, van Rijen PC, van Veelen CW, Ramsey NF. Language area localization with three-dimensional functional magnetic resonance imaging matches intrasulcular electrostimulation in Broca’s area. Ann Neurol. 1999;46:405–8.
Tomaiuolo F, MacDonald JD, Caramanos Z, et al. Morphology, morphometry and probability mapping of the pars opercularis of the inferior frontal gyrus: an in vivo MRI analysis. Eur J Neurosci. 1999;11:3033–46.
Benzagmout M, Gatignol P, Duffau H. Resection of World Health Organization Grade II gliomas involving Broca’s area: methodological and functional considerations. Neurosurgery. 2007;61:741–52.
Ojemann GA, Ojemann JG, Lettich E, Berger MS. Cortical language localization in left, dominant hemisphere: an electrical stimulation mapping investigation in 117 patients. J Neurosurg. 1989;71:316–26.
Sanai N, Mirzadeh Z, Berger MS. Functional outcome after language mapping for glioma resection. N Engl J Med. 2008;358:18–27.
Ojemann GA. Some brain mechanisms for reading. In: von Euler C, Lundberg I, Lennerstrand G, editors. Brain and reading. New York: MacMillan; 1989. p. 47–59.
Roux FE, Lubrano V, Lauwers-Cances V, et al. Intra-operative mapping of cortical areas involved in reading in mono- and bilingual patients. Brain. 2004;127:1796–810.
Ojemann JG, Ojemann GA, Lettich E. Cortical stimulation mapping of language cortex by using a verb generation task: effects of learning and comparison to mapping based on object naming. J Neurosurg. 2002;97:33–8.
Lubrano V, Roux FE, Demonet JF. Writing-specific sites in frontal areas: a cortical stimulation study. J Neurosurg. 2004;101:787–98.
Hamberger MJ, Goodman RR, Perrine K, Tamny T. Anatomic dissociation of auditory and visual naming in the lateral temporal cortex. Neurology. 2001;56:56–61.
Ojemann G, Mateer C. Human language cortex: localization of memory, syntax, and sequential motor-phoneme identification systems. Science. 1979;205:1401–3.
Schaffler L, Luders HO, Dinner DS, et al. Comprehension deficits elicited by electrical stimulation of Broca’s area. Brain. 1993;116:695–715.
Rapport RL, Tan CT, Whitaker HA. Language function and dysfunction among Chinese- and English-speaking polyglots: cortical stimulation, Wada testing, and clinical studies. Brain Lang. 1983;18:342–66.
Roux FE, Tremoulet M. Organization of language areas in bilingual patients: a cortical stimulation study. J Neurosurg. 2002;97:857–64.
Lucas TH, McKhann GM, Ojemann GA. Functional separation of languages in the bilingual brain: a comparison of electrical stimulation language mapping in 25 bilingual patients and 117 monolingual control patients. J Neurosurg. 2004;101:449–57.
Boatman D. Cortical bases of speech perception: evidence from functional lesion studies. Cognition. 2004;92:47–65.
Ojemann GA. Organization of short-term verbal memory in language areas of human cortex: evidence from electrical stimulation. Brain Lang. 1978;5:331–40.
Ojemann GA. Models of the brain organization for higher integrative functions derived with electrical stimulation techniques. Hum Neurobiol. 1982;1:243–9.
Fried I, Mateer C, Ojemann G, et al. Organization of visuospatial functions in human cortex. Evidence from electrical stimulation. Brain. 1982;105:349–71.
Kho KH, Rutten GJ, Leijten FS, et al. Working memory deficits after resection of the dorsolateral prefrontal cortex predicted by functional magnetic resonance imaging and electrocortical stimulation mapping. Case report. J Neurosurg. 2007;106:501–5.
Perrine K, Uysal S, Dogali M, et al. Functional mapping of memory and other nonlinguistic cognitive abilities in adults. Adv Neurol. 1993;63:165–77.
Thiebaut de Schotten M, Urbanski M, Duffau H, et al. Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans. Science. 2005;309:2226–8.
Roux FE, Boetto S, Sacko O, et al. Writing, calculating, and finger recognition in the region of the angular region: a cortical stimulation study of Gerstmann syndrome. J Neurosurg. 2003;99:716–27.
Boatman D, Gordon B, Hart J, et al. Transcortical sensory aphasia: revisited and revised. Brain. 2000;123:1634–42.
Martin A. The representation of object concepts in the brain. Annu Rev Psychol. 2007;58:25–45.
Lambon Ralph MA. Neural basis of memory. Brain mapping. Wien: Springer; 2012. p. 145–54.
Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci. 1986;9:357–81.
Sanai N, Berger MS. Operative techniques for gliomas and the value of extent of resection. Neurotherapeutics. 2009;6:478–86.
Skirboll SS, Ojemann GA, Berger MS, et al. Functional cortex and subcortical white matter located within gliomas. Neurosurgery. 1996;38:678–84.
Duffau H. The “frontal syndrome” revisited: lessons from electrostimulation mapping studies. Cortex. 2012;48:120–31.
Mandonnet E, Delattre JY, Tanguy ML, et al. Continuous growth of mean tumor diameter in a subset of grade II gliomas. Ann Neurol. 2003;53:524–8.
Schomas DA, Laack NN, Rao RD, et al. Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro-Oncology. 2009;11:437–45.
van den Bent MJ. Practice changing mature results of RTOG study 9802: another positive PCV trial makes adjuvant chemotherapy part of standard of care in low-grade glioma. Neuro-Oncology. 2014;16:1570–4.
Smith JS, Chang EF, Lamborn KR, et al. Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol. 2008;26:1338–45.
Sanai N, Berger MS. Glioma extent of resection and its impact on patient outcome. Neurosurgery. 2008;62:753–64.
Teunissen F, Verheul HB, Rutten GJ. Functionality of glioma-infiltrated precentral gyrus: experience from fourteen patients. J Neurosurg Sci. 2017;61(2):140–50.
Duffau H. Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity. Lancet Neurol. 2005;4:476–86.
Plaza M, Gatignol P, Leroy M, Duffau H. Speaking without Broca’s area after tumor resection. Neurocase. 2009;15:294–310.
Sarubbo S, Le Bars E, Moritz-Gasser S, Duffau H. Complete recovery after surgical resection of left Wernicke’s area in awake patient: a brain stimulation and functional MRI study. Neurosurg Rev. 2012;35:287–92; discussion 292.
Ungerleider LG, Haxby JV. ‘What’ and ‘where’ in the human brain. Curr Opin Neurobiol. 1994;4:157–65.
Duffau H, Thiebaut de Schotten M, Mandonnet E. White matter functional connectivity as an additional landmark for dominant temporal lobectomy. J Neurol Neurosurg Psychiatry. 2008;79:492–5.
Duffau H. The anatomo-functional connectivity of language revisited. New insights provided by electrostimulation and tractography. Neuropsychologia. 2008;46:927–34.
Sarubbo S, De Benedictis A, Maldonado IL, et al. Frontal terminations for the inferior fronto-occipital fascicle: anatomical dissection, DTI study and functional considerations on a multi-component bundle. Brain Struct Funct. 2011;218(1):21–37.
Martino J, Brogna C, Robles SG, et al. Anatomic dissection of the inferior fronto-occipital fasciculus revisited in the lights of brain stimulation data. Cortex. 2010;46(5):691–9.
Duffau H. Brain mapping: from neural basis of cognition to surgical applications. Wien: Springer; 2011.
Duffau H. Brain plasticity and tumors. Adv Tech Stand Neurosurg. 2008;33:3–33.
Sanai N, Polley MY, Berger MS. Insular glioma resection: assessment of patient morbidity, survival, and tumor progression. J Neurosurg. 2010;112:1–9.
Hebb AO, Yang T, Silbergeld DL. The sub-pial resection technique for intrinsic tumor surgery. Surg Neurol Int. 2011;2:180.
Dewarrat GM, Annoni JM, Fornari E, et al. Acute aphasia after right hemisphere stroke. J Neurol. 2009;256:1461–7.
Alexander MP, Fischette MR, Fischer RS. Crossed aphasias can be mirror image or anomalous. Case reports, review and hypothesis. Brain. 1989;112:953–73.
Zangwill OL. Speech and the minor hemisphere. Acta Neurol Psychiatr Belg. 1967;67:1013–20.
Gloning I, Gloning K, Haub G, Quatember R. Comparison of verbal behavior in right-handed and non right-handed patients with anatomically verified lesion of one hemisphere. Cortex. 1969;5:43–52.
Pedersen PM, Jorgensen HS, Nakayama H, et al. Aphasia in acute stroke: incidence, determinants, and recovery. Ann Neurol. 1995;38:659–66.
Wade DT, Hewer RL, David RM, Enderby PM. Aphasia after stroke: natural history and associated deficits. J Neurol Neurosurg Psychiatry. 1986;49:11–6.
Ross ED. Affective prosody and the aprosodias. In: Mesulam MM, editor. Principles of behavioral and cognitive neurology. 2nd ed. New York: Oxford University Press; 2000. p. 316–31.
Gazzaniga MS, Sperry RW. Language after section of the cerebral commissures. Brain. 1967;90:131–48.
Wada J. A new method for the determination of the side of cerebral speech dominance: a preliminary report on the intracarotid injection of sodium amytal in man. Igaku Seibutsugaku. 1949;14:221–2.
Loring DW, Meador KJ, Lee GP, King DW. Amobarbital effects and lateralized brain function: the Wada test. New York: Springer; 2012.
Hart Jr J, Lesser RP, Fisher RS, et al. Dominant-side intracarotid amobarbital spares comprehension of word meaning. Arch Neurol. 1991;48:55–8.
de Paola L, Mader MJ, Germiniani FM, et al. Bizarre behavior during intracarotid sodium amytal testing (Wada test): are they predictable? Arq Neuropsiquiatr. 2004;62:444–8.
Yetkin FZ, Swanson S, Fischer M, et al. Functional MR of frontal lobe activation: comparison with Wada language results. Am J Neuroradiol. 1998;19:1095–8.
Rasmussen T, Milner B. The role of early left-brain injury in determining lateralization of cerebral speech functions. Ann N Y Acad Sci. 1977;299:355–69.
Risse GL, Gates JR, Fangman MC. A reconsideration of bilateral language representation based on the intracarotid amobarbital procedure. Brain Cogn. 1997;33:118–32.
Kurthen M, Helmstaedter C, Linke DB, et al. Quantitative and qualitative evaluation of patterns of cerebral language dominance. An amobarbital study. Brain Lang. 1994;46:536–64.
Rutten GJ, Ramsey NF, van Rijen PC, et al. fMRI-determined language lateralization in patients with unilateral or bilateral language dominance according to the Wada test. NeuroImage. 2002;17:447–60.
Wyllie E, Luders H, Murphy D, et al. Intracarotid amobarbital (Wada) test for language dominance: correlation with results of cortical stimulation. Epilepsia. 1990;31:156–61.
Kho KH, Leijten FS, Rutten GJ, et al. Discrepant findings for Wada test and functional magnetic resonance imaging with regard to language function: use of electrocortical stimulation mapping to confirm results. Case report. J Neurosurg. 2005;102:169–73.
Duffau H, Lopes M, Arthuis F, et al. Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985-96) and with (1996-2003) functional mapping in the same institution. J Neurol Neurosurg Psychiatry. 2005;76:845–51.
Haglund MM, Berger MS, Shamseldin M, et al. Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery. 1994;34:567–76.
Borchers S, Himmelbach M, Logothetis N, Karnath HO. Direct electrical stimulation of human cortex—the gold standard for mapping brain functions? Nat Rev Neurosci. 2012;13:63–70.
Rutten GJ, Ramsey NF. The role of functional magnetic resonance imaging in brain surgery. Neurosurg Focus. 2010;28:E4.
Duffau H, Lopes M, Denvil D, Capelle L. Delayed onset of the supplementary motor area syndrome after surgical resection of the mesial frontal lobe: a time course study using intraoperative mapping in an awake patient. Stereotact Funct Neurosurg. 2001;76:74–82.
Krainik A, Duffau H, Capelle L, et al. Role of the healthy hemisphere in recovery after resection of the supplementary motor area. Neurology. 2004;62:1323–32.
Luders H, Lesser RP, Hahn J, et al. Basal temporal language area. Brain. 1991;114:743–54.
Ishitobi M, Nakasato N, Suzuki K, et al. Remote discharges in the posterior language area during basal temporal stimulation. Neuroreport. 2000;11:2997–3000.
Orwell G. Animal farm. 1st World Library—Literary Society; 2005.
Nathan SS, Sinha SR, Gordon B, et al. Determination of current density distributions generated by electrical stimulation of the human cerebral cortex. Electroencephalogr Clin Neurophysiol. 1993;86:183–92.
Mandonnet E, Winkler PA, Duffau H. Direct electrical stimulation as an input gate into brain functional networks: principles, advantages and limitations. Acta Neurochir. 2010;152(2):185–93.
Boisgueheneuc G, Levy R, Volle E, et al. Functions of the left superior frontal gyrus in humans: a lesion study. Brain. 2007;129:3315–28.
Luders H, Lesser RP, Dinner DS, et al. Localization of cortical function: new information from extraoperative monitoring of patients with epilepsy [published erratum appears in Epilepsia 1988 Nov-Dec;29(6):828]. Epilepsia. 1988;29(Suppl 2):S56–65.
Duffau H, Moritz-Gasser S, Mandonnet E. A re-examination of neural basis of language processing: proposal of a dynamic hodotopical model from data provided by brain stimulation mapping during picture naming. Brain Lang. 2013.
Luciani L, Tamburini A. Ricerche sperimentali sui centri psico-motori corticali; 1878.
Mills CK. Cerebral localization in its practical relations; 1888.
Krause F, Heymann E. Chirurgische Operationslehre des Kopfes. 1912;2.
Catani M, Stuss DT. At the forefront of clinical neuroscience. Cortex. 2012;48:1–6.
Rahm Jr WE, Scarff JE. Electrical stimulation of the cerebral cortex: description of a new stimulator. Arch Neurol Psychiatr. 1943;50:183–9.
Gill AS, Binder DK. Wilder Penfield, Pio del Rio-Hortega, and the discovery of oligodendroglia. Neurosurgery. 2007;60:940–8; discussion 940.
Penfield W. Cytology and cellular pathology of the nervous system. New York: Paul B Hoeber; 1932.
Sherman SM, Guillery RW. Functional connections of cortical areas: a new view from the thalamus. booksgooglecom; 2013.
Jelgersma G. Atlas anatomicum cerebri humani: 168 sections of the human brain. Amsterdam: Scheltema & Holkema; 1931.
Alexander M, Naeser M, Palumbo C. Correlations of subcortical CT lesion sites and aphasia profiles. Brain. 1987;110:961–88.
Murdoch BE. Speech and language disorders associated with subcortical pathology. Hoboken: Wiley; 2009.
Bates E. Plasticity, localization, and language development. The changing nervous system. Neurobehavioral consequences of early brain disorders. New York: Oxford University Press; 1999. p. 214–53.
Boatman DF, Miglioretti DL. Cortical sites critical for speech discrimination in normal and impaired listeners. J Neurosci. 2005;25:5475–80.
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Rutten, GJ. (2017). Mapping and Lesioning the Living Brain. In: The Broca-Wernicke Doctrine. Springer, Cham. https://doi.org/10.1007/978-3-319-54633-9_6
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