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Pharmacokinetic and Pharmacodynamics Relationships

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Book cover Imaging Infections

Abstract

PET imaging is likely to be a valuable tool for informing multi-compartment PK analysis by directly providing tissue drug concentration as a function of time, enabling a better understanding of the quantitative relationship between drug doses, time, and drug concentrations at the site of infection. Improved PK models coupled with real-time noninvasive PET imaging will support the design of drug regimens and allow the effect of drug dose on tissue drug concentrations to be directly monitored.

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Author information

Authors and Affiliations

  1. Institute for Chemical Biology and Drug Discovery, Department of Chemistry, Stony Brook University, Stony Brook, NY, USA

    Zhuo Zhang, Kayla R. Gogarty, Fereidoon Daryaee & Peter J. Tonge

  2. Department of Radiology, Stony Brook University School of Medicine, Stony Brook, NY, USA

    Zhuo Zhang, Kayla R. Gogarty, Fereidoon Daryaee & Peter J. Tonge

Authors
  1. Zhuo Zhang
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  2. Kayla R. Gogarty
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  3. Fereidoon Daryaee
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  4. Peter J. Tonge
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Corresponding author

Correspondence to Peter J. Tonge .

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Editors and Affiliations

  1. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Sanjay K. Jain

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Zhang, Z., Gogarty, K.R., Daryaee, F., Tonge, P.J. (2017). Pharmacokinetic and Pharmacodynamics Relationships. In: Jain, S. (eds) Imaging Infections . Springer, Cham. https://doi.org/10.1007/978-3-319-54592-9_9

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  • DOI: https://doi.org/10.1007/978-3-319-54592-9_9

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  • Publisher Name: Springer, Cham

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