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Molecular Epidemiology of Human Rotaviruses in Latin America

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Human Virology in Latin America

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Abstract

Rotavirus is the most common cause of acute diarrhea among infants and young children worldwide. Although rotaviruses pose a high burden in the Latin American population, massive rotavirus vaccination programs have been successfully implemented in this region. Extensive epidemiological analyses have shown that Latin American countries present a different distribution of rotavirus genotypes as compared with developed countries, with the predominant strain changing from season to season without any marked epidemiological pattern. Co-circulation and heterogeneous regional distributions of the rotavirus genotypes were also observed throughout the continent during pre- and post-vaccination programs. Currently, multiple efforts are being made to better understand rotavirus epidemiology and the effect of massive vaccination using state-of-the-art molecular techniques. This information will help in evaluating the efficacy of the current rotavirus vaccine in the different Latin American countries.

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Authors and Affiliations

  1. Laboratorio Nacional de Referencia para Rotavirus y Norovirus, Instituto Nacional de Enfermedades Infecciosas ANLIS (“Dr. Carlos G. Malbrán”), Buenos Aires, Argentina

    Juan I. Degiuseppe & Juan A. Stupka

  2. Division of Viral Products, Food and Drug Administration, Silver Spring, MD, USA

    Gabriel I. Parra

Authors
  1. Juan I. Degiuseppe
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  2. Juan A. Stupka
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  3. Gabriel I. Parra
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Correspondence to Gabriel I. Parra .

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Editors and Affiliations

  1. Instituto Politécnico Nacional, Center for Research and Advances Studies, Mexico City, Mexico

    Juan Ernesto Ludert

  2. Centro de Microbiologia y Biologia Celular, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Venezuela

    Flor H. Pujol

  3. Facultad de Ciencias, Universidad de la Republica, Montevideo, Uruguay

    Juan Arbiza

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Degiuseppe, J.I., Stupka, J.A., Parra, G.I. (2017). Molecular Epidemiology of Human Rotaviruses in Latin America. In: Ludert, J., Pujol, F., Arbiza, J. (eds) Human Virology in Latin America. Springer, Cham. https://doi.org/10.1007/978-3-319-54567-7_5

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