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Outline: Pediatric Venous Thromboembolism

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Patient Safety and Quality in Pediatric Hematology/Oncology and Stem Cell Transplantation

Abstract

The rate of venous thromboembolism (VTE) in hospitalized pediatric patients is increasing and is considered the second most common contributor to harm in hospitalized pediatric patients. These thrombotic events are multifactorial in origin, with the presence of a central venous catheter as the dominant risk factor. VTE associated harms are significant and range from pain at the site of thrombosis to life-threatening pulmonary embolism. Some of these thrombotic events in the highest risk patients are thought to be preventable through adequate risk assessment and the application of thromboprophylactic measures. Pediatric patients with certain oncologic and hematologic disorders are at high risk for VTE and should be targeted for preventative interventions. Effective strategies to reduce VTE include accurately tracking VTE incidence, effectively screening each patient for their VTE risk, and implementing VTE preventative measures including mechanical and/or medical prophylaxis for those patients at high risk.

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Authors and Affiliations

  1. Division of Hematology/Oncology, Children’s Hospital Los Angeles, 4650 Sunset Blvd, Mailstop #54, Los Angeles, CA, 90027, USA

    Julie Jaffray

  2. Division of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Char Witmer

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Correspondence to Julie Jaffray .

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Editors and Affiliations

  1. Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

    Christopher E. Dandoy

  2. Center for Cancer and Blood Disorders, Children’s Hospital Colorado, Aurora, Colorado, USA

    Joanne M. Hilden

  3. Boston Children’s Cancer and Blood Disorders Center, Dana-Farber, Boston, Massachusetts, USA

    Amy L. Billett

  4. Johns Hopkins All Children’s Hospital, St. Petersburg, Florida, USA

    Brigitta U. Mueller

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Jaffray, J., Witmer, C. (2017). Outline: Pediatric Venous Thromboembolism. In: Dandoy, C., Hilden, J., Billett, A., Mueller, B. (eds) Patient Safety and Quality in Pediatric Hematology/Oncology and Stem Cell Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-53790-0_12

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